Amniocentesis removes a small amount of fluid from the sac around the baby in the womb (uterus). It is most often done in a doctor's office or medical center. You do not need to stay in the hospital.

You will have a pregnancy ultrasound first. This helps your health care provider see where the baby is in your womb.

Numbing medicine is then rubbed onto part of your belly. Sometimes, the medicine is given through a shot in the skin on the belly area. The skin is cleaned with a disinfecting liquid.

Your provider inserts a long, thin needle through your belly and into your womb. A small amount of fluid (about 4 teaspoons or 20 milliliters) is removed from the sac surrounding the baby. In most cases, the baby is watched by ultrasound during the procedure.

The fluid is sent to a laboratory. Testing may include:

• Genetic studies
• Measurement of alpha-fetoprotein (AFP) levels (a substance produced in the liver of the developing baby)
• Culture for infection

Results of genetic testing usually take about 2 weeks. Other test results come back in 1 to 3 days.

Sometimes amniocentesis is also used later in pregnancy to:

• Diagnose infection
• Check whether the baby's lungs are developed and ready for delivery
• Remove excess fluid from around the baby if there is too much amniotic fluid (polyhydramnios)

  Polyhydramnios

  Polyhydramnios occurs when too much amniotic fluid builds up during pregnancy. It is also called amniotic fluid disorder, or hydramnios.

  

  Image

  ##RemoveMe##

  Read Article Now Book Mark Article

Your bladder may need to be full for the ultrasound. Check with your provider about this.

Before the test, blood may be taken to find out your blood type and Rh factor. You may get a shot of medicine called Rho(D) Immune Globulin (RhoGAM and other brands) if you are Rh negative.

Amniocentesis is usually offered to women who are at increased risk of having a child with birth defects. This includes women who:

• Will be 35 or older when they give birth
• Had a screening test that shows there may be a birth defect or other problem
• Have had babies with birth defects in other pregnancies
• Have a family history of genetic disorders

Genetic counseling is recommended before the procedure. This will allow you to:

• Learn about other prenatal tests
• Make an informed decision about options for prenatal diagnosis

This test:

• Is a diagnostic test, not a screening test
• Is greater than 99% accurate for diagnosing Down syndrome
• Is most often done between 15 to 20 weeks, but can be performed at any time between 15 to 40 weeks

Amniocentesis can be used to diagnose many different gene and chromosome problems in the baby, including:

• Anencephaly (when the baby is missing a large portion of the brain)
• Down syndrome
• Rare metabolic disorders that are passed down through families
• Other genetic problems, like trisomy 18
• Infections in the amniotic fluid

A normal result means:

• No genetic or chromosome problems were found in your baby.
• Bilirubin and alpha-fetoprotein levels appear normal.
• No signs of infection were found.

Note: Amniocentesis typically is the most accurate test for genetic conditions and malformation, Although rare, a baby may still have genetic or other types of birth defects, even if amniocentesis results are normal.

An abnormal result may mean your baby has:

• A gene or chromosome problem, such as Down syndrome

  Down syndrome

  Down syndrome is a genetic condition in which a person has 47 chromosomes instead of the usual 46.

  ##RemoveMe##

  Read Article Now Book Mark Article
• Birth defects that involve the spine or brain, such as spina bifida

Talk to your provider about the meaning of your specific test results. Ask your provider:

• How the condition or defect may be treated during or after your pregnancy
• What special needs your child may have after birth
• What other options you have about maintaining or ending your pregnancy

Risks are minimal, but may include:

• Infection or injury to the baby
• Miscarriage

  Miscarriage

  A miscarriage is the spontaneous loss of a fetus before the 20th week of pregnancy (pregnancy losses after the 20th week are called stillbirths). Mi...

  

  Image

  ##RemoveMe##

  Read Article Now Book Mark Article
• Leaking of amniotic fluid
• Vaginal bleeding