Campylobacter serology test
Campylobacter serology test is a blood test to look for antibodies to bacteria called campylobacter.
Antibodies
An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens. Examples of antigens include micr...
How the Test is Performed
A blood sample is needed.
Blood sample
Venipuncture is the collection of blood from a vein. It is most often done for laboratory testing.
The sample is sent to a lab. There, tests are done to look for antibodies to campylobacter. Antibody production increases during the infection. When the illness first starts, few antibodies are detected. For this reason, blood tests need to be repeated 10 days to 2 weeks later.
How to Prepare for the Test
There is no special preparation.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
This test detects the presence of antibodies to campylobacter in the blood. Campylobacter infection can cause diarrheal illness. A blood test is rarely done to diagnose campylobacter diarrheal illness. It is used if your health care provider thinks you are having complications from this infection, such as reactive arthritis or Guillain-Barré syndrome .
Campylobacter infection
Campylobacter infection occurs in the small intestine from a bacteria called Campylobacter jejuni. It is a type of food poisoning.
Reactive arthritis
Reactive arthritis is a group of conditions that may involve the joints, eyes, and urinary and genital systems. These areas become swollen and infla...
Guillain-Barré syndrome
Guillain-Barré syndrome is a serious health problem that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system...
Normal Results
A normal test result means no antibodies to campylobacter are present. This is called a negative result.
Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results.
What Abnormal Results Mean
An abnormal (positive) result means that antibodies against campylobacter have been detected. This means you have come in contact with the bacteria.
Tests are often repeated during the course of an illness to detect a rise in antibody levels. This rise helps to confirm an active infection. A low level may be a sign of a previous infection rather than current disease.
Risks
Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling lightheaded
- Hematoma (blood buildup under the skin)
- Infection (a slight risk any time the skin is broken)
References
Allos BM. Campylobacter infections. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 303.
Allos BM, Iovine NM, Blaser MJ. Campylobacter jejuni and related species. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 218.
Haines CF, Sears CL. Infectious enteritis and proctocolitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 110.
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Blood test - illustration
Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.
Blood test
illustration
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Campylobacter jejuni organism - illustration
Campylobacter jejuni Campylobacter jejuni Campylobacter jejuni
Campylobacter jejuni organism
illustration
-
Blood test - illustration
Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.
Blood test
illustration
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Campylobacter jejuni organism - illustration
Campylobacter jejuni Campylobacter jejuni Campylobacter jejuni
Campylobacter jejuni organism
illustration
Review Date: 3/13/2016
Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.