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Bronchopulmonary dysplasia

BPD; Chronic lung disease - children; CLD - children

 

Bronchopulmonary dysplasia (BPD) is a chronic lung condition that affects newborn babies who were either put on a breathing machine after birth or were born very early (prematurely).

Causes

 

BPD occurs in very ill infants who received high levels of oxygen for a long period. BPD can also occur in infants who were on a breathing machine ( ventilator ).

BPD is more common in infants born early (prematurely), whose lungs were not fully developed at birth.

Risk factors include:

  • Congenital heart disease
  • Prematurity, usually in infants born before 32 weeks gestation
  • Severe respiratory or lung infection

Risk of severe BPD has decreased in recent years.

 

Symptoms

 

Symptoms may include any of the following:

  • Bluish skin color (cyanosis)
  • Cough
  • Rapid breathing
  • Shortness of breath

 

Exams and Tests

 

Tests that may be done to help diagnose BPD include

  • Arterial blood gas
  • Chest CT scan
  • Chest x-ray
  • Pulse oximetry

 

Treatment

 

IN THE HOSPITAL

Infants who have breathing problems are often put on a ventilator. This is a breathing machine that sends pressure to the baby's lungs to keep them inflated and to deliver more oxygen. As the baby's lungs develop, the pressure and oxygen are slowly reduced. The baby is weaned from the ventilator. The baby may continue to get oxygen by a mask or nasal tube for several weeks or months.

Infants with BPD are usually fed by tubes inserted into the stomach (NG tube) . These babies need extra calories due to the effort of breathing. To keep their lungs from filling with fluid, their fluid intake may need to be limited. They may also be given medicines that remove water from the body (diuretics). Other medicines can include corticosteroids, bronchodilators, and surfactant.

Parents of these infants need emotional support. This is because BPD takes time to get better and the infant may need to stay in the hospital for a long time.

AT HOME

Infants with BPD may need oxygen therapy for weeks to months after leaving the hospital. Follow your health care provider's instructions to ensure your baby gets enough nutrition during recovery. Your baby may need tube feedings or special formulas.

It is very important to prevent your baby from getting colds and other infections, such as respiratory syncytial virus (RSV). RSV can cause a severe lung infection, especially in a baby with BPD.

A simple way to help prevent RSV infection is to wash your hands often. Follow these measures:

  • Wash your hands with warm water and soap before touching your baby. Tell others to wash their hands, too, before touching your baby.
  • Ask others to avoid contact with your baby if they have a cold or fever, or ask them to wear a mask.
  • Be aware that kissing your baby can spread RSV.
  • Try to keep young children away from your baby. RSV is very common among young children and spreads easily from child-to-child.
  • DO NOT smoke inside your house, car, or anywhere near your baby. Exposure to tobacco smoke increases the risk of RSV illness.

Parents of babies with BPD should avoid crowds during outbreaks of RSV. Outbreaks are often reported by local news media.

Your baby's provider may prescribe the medicine palivizumab (Synagis) to prevent RSV infection in your baby. Follow instructions on how to give your baby this medicine.

 

Outlook (Prognosis)

 

Babies with BPD get better slowly over time. Oxygen therapy may be needed for many months. Some infants have long-term lung damage and require oxygen and breathing support, such as with a ventilator. Some infants with this condition may not survive.

 

Possible Complications

 

Babies who have had BPD are at greater risk of repeated respiratory infections, such as pneumonia , bronchiolitis , and respiratory syncytial virus (RSV) that require a hospital stay.

Other possible complications in babies who have had BPD are:

  • Developmental problems
  • Poor growth
  • Pulmonary hypertension

 

When to Contact a Medical Professional

 

If your baby had BPD, watch for any breathing problems . Call your health care provider if you see any signs of a respiratory infection.

 

Prevention

 

To help prevent BPD:

  • Prevent premature delivery whenever possible. If you are pregnant or thinking about getting pregnant, get prenatal care to help keep you and your baby healthy.
  • If your baby is on breathing support, ask the provider how soon your baby can be weaned from the ventilator.
  • Your baby may receive a substance called surfactant to help keep the baby's lungs open.

 

 

Open References

References

Bancalari EH, Walsh MC. Bronchopulmonary dysplasia in the neonate. In: Martin RJ, Fanaroff AA, Walsh MC. Fanaroff and Martin's Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 10th ed. Philadelphia, PA: Elsevier Mosby; 2015:chap 77.

Lestrud SO. Bronchopulmonary dysplasia. In: Kliegman RM, Stanton BF, St. Geme J, Schor NF, Behrman RE, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 416.

 

        A Closer Look

         

          Self Care

           

          Tests for Bronchopulmonary dysplasia

           
             

            Review Date: 6/22/2015

            Reviewed By: Denis Hadjiliadis, MD, MHS, Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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