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    Occupational Asthma

    Asthma - occupational exposure; Irritant-induced reactive airways disease

    Occupational asthma is a lung disorder in which substances found in the workplace cause the airways of the lungs to swell and narrow. This leads to attacks of wheezing, shortness of breath, chest tightness, and coughing.


    Asthma is caused by inflammation (swelling) in the airways of the lungs. When an asthma attack occurs, the lining of the air passages swells and the muscles surrounding the airways become tight. This reduces the amount of air that can pass by.

    Inpersons who have sensitive airways, asthma symptoms can be triggered by breathing in substances called triggers.

    Many substances in the workplace can trigger asthma symptoms, leading to occupational asthma. The most common triggers are wood dust, grain dust, animal dander, fungi, or chemicals.

    The following workers are at higher risk:

    • Bakers
    • Detergent manufacturers
    • Drug manufacturers
    • Farmers
    • Grain elevator workers
    • Laboratory workers (especially those working with laboratory animals)
    • Metal workers
    • Millers
    • Plastics workers
    • Woodworkers


    Symptoms are usually due tonarrowing of the airways and tightening spasms of the muscles lining the airways. This reduces the amount of air that can pass through and it can lead to wheezing sounds.

    Symptoms usually occur shortly after you are exposed to the substance. They often improve or go away when you leave work. Some people may not have symptoms until 12 or more hours after being exposed to the allergen.

    Symptoms usually get worse toward the end of the work week and may go away on weekends or vacations.

    Symptoms include:

    • Coughing
    • Tight feeling in the chest
    • Shortness of breath
    • Wheezing

    The health care provider will perform a physical exam and ask about your medical history. Your symptoms may have a pattern of getting worse with a certain workplace environment or substance.

    The health care provider will listen to your lungs with a stethoscope to check for wheezing.

    Tests may beordered toconfirm diagnosis:

    • Blood tests to look for antibodies to the substance
    • Bronchial provocation test (test measuring reaction to the suspected allergen)
    • Chest x-ray
    • Complete blood count
    • Peak expiratory flow rate
    • Pulmonary function tests


    Avoiding exposure to the substance that is causing your asthma is the best treatment.

    Measures may include:

    • Changing jobs (though this may be difficult to do)
    • Moving to a different location at thework sitewhere there is less exposure to the substance. This may help, but over time, even a very small amount of the substance can trigger an asthma attack.
    • Using a respiratory device to protect or reduce your exposure may help.

    Asthma medicines may help manage your symptoms.

    Your doctor may prescribe:

    • Asthma quick-relief medicines, called bronchodilators, to help relax the muscles of your airways.
    • Asthma control medicines that are taken every day to prevent symptoms.

    Outlook (Prognosis)

    Occupational asthma may keep getting worse if you continue to be exposed to the substance that is causing the problem, even if medicines improve your symptoms. You may need to change jobs.

    Sometimes, symptoms may continue even when the substance is removed.

    In general, the outcome for people with asthma is good. However, symptoms may continue for years after you are no longer exposed in the workplace.

    When to Contact a Medical Professional

    Call your health care provider if you have symptoms of asthma.


    Chan-Yeung M, Malo JL. Asthma in the workplace and occupational asthma. In: Mason RJ, Broaddus VC, Martin TR, et al., eds. Murray & Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa.: Elsevier Saunders; 2010:chap 64.

    Cowl CT. Occupational asthma: review of assessment, treatment, and compensation. Chest. 2011;139:674-681.


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            Tests for Occupational Asthma

              Review Date: 5/23/2013

              Reviewed By: Paula J. Busse, MD, Assistant Professor of Medicine, Division of Clinical Immunology, Mount Sinai School of Medicine, New York, NY, Review provided by VeriMed Healthcare Network.

              The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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