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Pulmonary actinomycosis

Actinomycosis - pulmonary; Actinomycosis - thoracic

 

Pulmonary actinomycosis is a rare lung infection caused by bacteria.

Causes

 

Pulmonary actinomycosis is caused by certain bacteria normally found in the mouth and gastrointestinal tract. The bacteria often do not cause harm. But poor dental hygiene and tooth abscess can increase your risk for lung infections caused by these bacteria.

People with the following health problems also have a higher chance of developing the infection:

  • Alcohol use
  • Scars on the lungs ( bronchiectasis )
  • COPD

The disease is rare in the United States. It may occur at any age, but is most common in people 30 to 60 years old. Men get this infection more often than women.

 

Symptoms

 

The infection often comes on slowly. It may be weeks or months before diagnosis is confirmed.

Symptoms may include any of the following:

  • Chest pain when taking a deep breath
  • Cough with phlegm (sputum)
  • Fever
  • Lethargy
  • Night sweats
  • Shortness of breath
  • Weight loss

 

Exams and Tests

 

The health care provider will perform a physical exam, and ask about your medical history and symptoms. Tests that may be done include:

  • Bronchoscopy with culture
  • Complete blood count (CBC)
  • Chest x-ray
  • Chest CT scan
  • Lung biopsy
  • Modified AFB smear of sputum
  • Sputum culture
  • Tissue and sputum Gram stain
  • Thoracentesis with culture
  • Tissue culture

 

Treatment

 

The goal of treatment is to cure the infection. It may take a long time to get better. To be cured, you may need to receive the antibiotic penicillin through a vein (intravenously) for 4 to 6 weeks. Then you need to take penicillin by mouth for a long period. Some people need up to 18 months of antibiotic treatment.

If you cannot take penicillin, your provider will prescribe other antibiotics.

Surgery may be needed to drain fluid from the lungs and control the infection.

 

Outlook (Prognosis)

 

Most people get better after treatment with antibiotics.

 

Possible Complications

 

Complications may include:

  • Brain abscess
  • Destruction of parts of the lungs
  • Emphysema
  • Meningitis
  • Osteomyelitis (bone infection)

 

When to Contact a Medical Professional

 

Call your provider if:

  • You have symptoms of pulmonary actinomycosis
  • Your symptoms get worse or do not improve with treatment
  • You develop new symptoms
  • You have a fever of 101°F (38.3°C) or higher.

 

Prevention

 

Good dental hygiene may help reduce your risk for actinomycosis.

 

 

References

Brook I. Actinomycosis. In: Goldman L, Schafer AI. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 329.

Russo TA. Agents of actinomycosis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 256.

Torres A, Menendez R, Wunderink RG. Bacterial pneumonia and lung abscess. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 33.

 
  • Respiratory system - illustration

    Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.

    Respiratory system

    illustration

    • Respiratory system - illustration

      Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.

      Respiratory system

      illustration

    A Closer Look

     

      Talking to your MD

       

        Self Care

         

          Tests for Pulmonary actinomycosis

           

             

            Review Date: 3/13/2016

            Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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