Toxoplasma blood test
Toxoplasma serology; Toxoplasma antibody titer
The toxoplasma blood test looks for antibodies in the blood to a parasite called Toxoplasma gondii .
Antibodies
An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens. Examples of antigens include micr...
How the Test is Performed
Blood sample is needed
Venipuncture is the collection of blood from a vein. It is most often done for laboratory testing.
How to Prepare for the Test
There is no special preparation for the test.
How the Test will Feel
When the needle is inserted to draw blood, some people may feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
The test is done when the health care provider suspects that you have toxoplasmosis . The infection is a danger to a developing baby if a pregnant woman gets infected. It is also dangerous in people with HIV/AIDS .
Toxoplasmosis
Toxoplasmosis is an infection due to the parasite Toxoplasma gondii.
HIV/AIDS
Human immunodeficiency virus (HIV) is the virus that causes AIDS. When a person becomes infected with HIV, the virus attacks and weakens the immune ...
In pregnant women, the test is done to:
- Check if a woman has a current infection or had an infection in the past.
- Check if the baby has the infection.
The presence of antibodies before pregnancy probably protects a developing baby against toxoplasmosis at birth. But antibodies that develop during pregnancy may mean the mother and baby are infected. This infection during pregnancy increases the risk for miscarriage or birth defects.
Antibodies
An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens. Examples of antigens include micr...
This test may also be done if you have:
- An unexplained lymph node swelling
- An unexplained rise in the blood white cell (lymphocyte) count
- HIV and have symptoms of a toxoplasmosis of the brain (including headache, seizures, weakness, and speech or vision problems)
- Inflammation of the back part of the eye (chorioretinitis)
Normal Results
Normal results mean you have likely never had a toxoplasma infection.
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test result.
What Abnormal Results Mean
Abnormal results mean that you have probably been infected with the parasite. Two types of antibodies are measured, IgM and IgG:
- If level of IgM antibodies are raised, you likely became infected in the recent past.
- If level of IgG antibodies are raised, you became infected sometime in the past.
Risks
Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
- Excessive bleeding
- Fainting or feeling lightheaded
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
References
Fritsche TR, Selvarangan R. Medical parasitology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods . 22nd ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 62.
Montoya JG, Boothroyd JC, Kovacs JA. Toxoplasma gondii . In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases . 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 280.
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Blood test - illustration
Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.
Blood test
illustration
-
Blood test - illustration
Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.
Blood test
illustration
Review Date: 9/10/2015
Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.