Pupil - white spots
Leukocoria
White spots in the pupil is a condition that causes the pupil of the eye to look white instead of black.
Considerations
The pupil of the human eye is normally black. In flash photographs the pupil may appear red. This is called the "red reflex" by health care providers and is normal.
Sometimes, the pupil of the eye may appear white, or the normal red reflex may appear to be white. This not a normal condition, and you need to see an eye care provider right away.
There are many different causes of white pupil or white reflex. Other conditions also can mimic white pupil. If the cornea, which is normally clear, becomes cloudy, it may look similar to a white pupil. Although the causes of a cloudy or white cornea are different from those of a white pupil or white reflex, these problems also need medical attention right away.
Cataracts may also cause the pupil to appear white.
Causes
Causes of this condition may include:
- Coats' disease - exudative retinopathy
-
Coloboma
Coloboma
Coloboma of the iris is a hole or defect of the iris of the eye. Most colobomas are present since birth (congenital).
-
Congenital cataract
(may be hereditary or may result from other conditions, including
congenital rubella
,
galactosemia
,
retrolental fibroplasia
)
Congenital cataract
A congenital cataract is a clouding of the lens of the eye that is present at birth. The lens of the eye is normally clear. It focuses light that c...
Congenital rubella
Congenital rubella is a condition that occurs in an infant whose mother is infected with the virus that causes German measles. Congenital means the ...
Galactosemia
Galactosemia is a condition in which the body is unable to use (metabolize) the simple sugar galactose.
Retrolental fibroplasia
Retinopathy of prematurity (ROP) is abnormal blood vessel development in the retina of the eye. It occurs in infants that are born too early (premat...
- Persistent primary hyperplastic vitreous
-
Retinoblastoma
Retinoblastoma
Retinoblastoma is a rare, cancerous tumor of a part of the eye called the retina.
- Toxocara canis (infection caused by a parasite)
-
Uveitis
Uveitis
Uveitis is swelling and irritation of the uvea. The uvea is the middle layer of the eye. The uvea provides most of the blood supply to the retina....
Home Care
Most causes of white pupil will cause decreased vision. This may often occur before the pupil appears to be white.
Detecting a white pupil is especially important in infants. Babies are unable to communicate to others that their vision is decreased. It is also harder to measure an infant's vision during an eye exam.
If you see a white pupil, call your health care provider right away. Well-child exams routinely screen for a white pupil in children. A child that develops a white pupil or cloudy cornea needs immediate attention, preferably from an eye specialist.
It is important to get diagnosed early if the problem is caused by retinoblastoma since this disease can be fatal.
When to Contact a Medical Professional
Contact your health care provider if you notice any color changes in the pupil or cornea of the eye.
What to Expect at Your Office Visit
The health care provider will do a physical exam and ask about your symptoms and medical history.
The physical exam will include a detailed eye examination.
The following tests may be performed:
-
Ophthalmoscopy
Ophthalmoscopy
Ophthalmoscopy is an examination of the back part of the eye (fundus), which includes the retina, optic disc, choroid, and blood vessels.
-
Slit-lamp exam
Slit-lamp exam
The slit-lamp examination looks at structures that are at the front of the eye.
-
Standard eye exam
Standard eye exam
A standard ophthalmic exam is a series of tests done to check your vision and the health of your eyes.
-
Visual acuity
Visual acuity
The visual acuity test is used to determine the smallest letters you can read on a standardized chart (Snellen chart) or a card held 20 feet (6 meter...
Other tests may that be done include a head CT or MRI scan .
Head CT
A head computed tomography (CT) scan uses many x-rays to create pictures of the head, including the skull, brain, eye sockets, and sinuses.
MRI scan
A magnetic resonance imaging (MRI) scan is an imaging test that uses powerful magnets and radio waves to create pictures of the body. It does not us...
References
Olitsky SE, Hug D, Plummer LS, Stahl ED, et al. Examination of the eye. In: Kliegman RM, Stanton BF, St Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016:chap 619.
Shields CL, Shields JA. Retinoblastoma. In: Tasman W, Jaeger EA, eds. Duane's Ophthalmology . 2013 ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:vol 3;chap 35.
Yanoff M, Cameron D. Disease of the visual system. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 423.
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Eye - illustration
The eye is the organ of sight, a nearly spherical hollow globe filled with fluids (humors). The outer layer or tunic (sclera, or white, and cornea) is fibrous and protective. The middle tunic layer (choroid, ciliary body and the iris) is vascular. The innermost layer (the retina) is nervous or sensory. The fluids in the eye are divided by the lens into the vitreous humor (behind the lens) and the aqueous humor (in front of the lens). The lens itself is flexible and suspended by ligaments which allow it to change shape to focus light on the retina, which is composed of sensory neurons.
Eye
illustration
-
White spots in the pupil - illustration
On occasion, the pupil of the eye may appear white. This is never a normal condition and requires immediate evaluation by an ophthalmologist. The causes of a cloudy or white cornea are different than those of a white pupil but are also significant and require immediate attention. Cataracts can also cause the pupil to appear white.
White spots in the pupil
illustration
-
White pupil - illustration
The normal appearance of the pupil of the human eye is black. The appearance of a white pupil is never a normal condition and requires immediate evaluation by specialists trained in ophthalmology. A cloudy cornea or cataract may be mistaken for a white pupil, but usually a white pupil is due to infection or disease.
White pupil
illustration
-
Eye - illustration
The eye is the organ of sight, a nearly spherical hollow globe filled with fluids (humors). The outer layer or tunic (sclera, or white, and cornea) is fibrous and protective. The middle tunic layer (choroid, ciliary body and the iris) is vascular. The innermost layer (the retina) is nervous or sensory. The fluids in the eye are divided by the lens into the vitreous humor (behind the lens) and the aqueous humor (in front of the lens). The lens itself is flexible and suspended by ligaments which allow it to change shape to focus light on the retina, which is composed of sensory neurons.
Eye
illustration
-
White spots in the pupil - illustration
On occasion, the pupil of the eye may appear white. This is never a normal condition and requires immediate evaluation by an ophthalmologist. The causes of a cloudy or white cornea are different than those of a white pupil but are also significant and require immediate attention. Cataracts can also cause the pupil to appear white.
White spots in the pupil
illustration
-
White pupil - illustration
The normal appearance of the pupil of the human eye is black. The appearance of a white pupil is never a normal condition and requires immediate evaluation by specialists trained in ophthalmology. A cloudy cornea or cataract may be mistaken for a white pupil, but usually a white pupil is due to infection or disease.
White pupil
illustration
Review Date: 11/4/2015
Reviewed By: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.