Memory loss
Forgetfulness; Amnesia; Impaired memory; Loss of memory; Amnestic syndrome; Dementia - memory loss; Mild cognitive impairment - memory loss
Memory loss (amnesia) is unusual forgetfulness. You may not be able to remember new events, recall one or more memories of the past, or both.
The memory loss may be for a short time and then resolve (transient). Or, it may not go away, and, depending on the cause, it can get worse over time.
Causes
Normal aging can cause some forgetfulness. It is normal to have some trouble learning new material or needing more time to remember it. But normal aging does not lead to dramatic memory loss. Such memory loss is due to other diseases.
Memory loss can be caused by many things. To determine a cause, your health care provider will ask if the problem came on suddenly or slowly.
Many areas of the brain help you create and retrieve memories. A problem in any of these areas can lead to memory loss.
Memory loss may result from a new injury to the brain, which is caused by or is present after:
-
Brain tumor
Brain tumor
A primary brain tumor is a group (mass) of abnormal cells that start in the brain.
-
Cancer treatment, such as
brain radiation
,
bone marrow transplant
, or
chemotherapy
Brain radiation
Radiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells.
Bone marrow transplant
A bone marrow transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Bone marrow is the soft, fat...
Chemotherapy
The term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancerShrink the cancerPrevent the cancer from ...
-
Concussion
or head trauma
Concussion
A concussion may occur when the head hits an object, or a moving object strikes the head. A concussion is a minor or less severe type of brain injur...
The term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancerShrink the cancerPrevent the cancer from ...
- Not enough oxygen getting to the brain when your heart or breathing is stopped for too long
-
Severe
brain infection
or
infection around brain
Brain infection
Encephalitis is irritation and swelling (inflammation) of the brain, most often due to infections.
Infection around brain
Meningitis is an infection of the membranes covering the brain and spinal cord. This covering is called the meninges.
- Major surgery or severe illness, including brain surgery
- Transient global amnesia (sudden, temporary loss of memory) of unclear cause
-
Transient ischemic attack (TIA)
or
stroke
A transient ischemic attack occurs when blood flow to a part of the brain stops for a brief time. A person will have stroke-like symptoms for up to ...
Transient ischemic attack (TIA)
A transient ischemic attack occurs when blood flow to a part of the brain stops for a brief time. A person will have stroke-like symptoms for up to ...
Stroke
A stroke occurs when blood flow to a part of the brain stops. A stroke is sometimes called a "brain attack. " If blood flow is cut off for longer th...
- Hydrocephalus (fluid collection in the brain)
Sometimes, memory loss occurs with mental health problems, such as:
- After a major, traumatic or stressful event
-
Bipolar disorder
Bipolar disorder
Bipolar disorder is a mental condition in which a person has wide or extreme swings in their mood. Periods of feeling sad and depressed may alternat...
-
Depression
or other mental health disorders, such as
schizophrenia
Depression
Depression is feeling sad, blue, unhappy, or down in the dumps. Most people feel this way once in a while. Major depression is a mood disorder. It...
Schizophrenia
Schizophrenia is a mental disorder that makes it hard to tell the difference between what is real and not real. It also makes it hard to think clearl...
Memory loss may be a sign of dementia . Dementia also affects thinking, language, judgment, and behavior.
Dementia
Dementia is a loss of brain function that occurs with certain diseases. It affects memory, thinking, language, judgment, and behavior.
Other causes of memory loss include:
- Alcohol or use of prescription or illegal drugs
-
Brain infections such as
Lyme disease
, syphilis, or HIV/AIDS
Lyme disease
Lyme disease is a bacterial infection that is spread through the bite of one of several types of ticks.
-
Overuse of medicines, such as barbiturates or (
hypnotics
)
Hypnotics
Benzodiazepines; Sedatives; Hypnotics; Sleeping pills; Insomnia - medicines; Sleep disorder - medicines
- ECT (electroconvulsive therapy) (most often short-term memory loss)
-
Epilepsy
that is not well controlled
Epilepsy
Epilepsy is a brain disorder in which a person has repeated seizures over time. Seizures are episodes of uncontrolled and abnormal firing of brain c...
-
Illness that results in the loss of, or damage to brain tissue or nerve cells, such as
Parkinson disease
,
Huntington disease
, or
multiple sclerosis
Parkinson disease
Parkinson disease causes certain brain cells to die. These are the cells that help control movement and coordination. The disease leads to shaking ...
Huntington disease
Huntington disease is a disorder in which nerve cells in certain parts of the brain waste away, or degenerate. The disease is passed down through fa...
Multiple sclerosis
Multiple sclerosis is an autoimmune disease that affects the brain and spinal cord (central nervous system).
-
Low levels of important nutrients or vitamins, such as low vitamin B1 or
B12
B12
Vitamin B12 is a water-soluble vitamin. Water-soluble vitamins dissolve in water. After the body uses these vitamins, leftover amounts leave the bo...
Home Care
A person with memory loss needs a lot of support.
- It helps to show the person familiar objects, music, or and photos or play familiar music.
- Write down when the person should take any medicine or do other important tasks. It is important to write it down.
- If a person needs help with everyday tasks, or if safety or nutrition is a concern, you may want to consider extended-care facilities, such as a nursing home.
What to Expect at Your Office Visit
The provider will perform a physical exam and ask about the person's medical history and symptoms. This will usually include asking questions of family members and friends. For this reason, they should come to the appointment.
Medical history questions may include:
- Type of memory loss, such as short-term or long-term
- Time pattern, such as how long the memory loss has lasted or whether it comes and goes
- Things that triggered memory loss, such as head injury or surgery
Tests that may be done include:
- Blood tests for specific diseases that are suspected (such as low vitamin B12 or thyroid disease)
-
Cerebral angiography
Cerebral angiography
Cerebral angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the brain.
-
Cognitive tests
(neuropsychological/psychometric tests)
Cognitive tests
Mental status testing is done to check a person's thinking ability, and to determine if any problems are getting better or worse. It is also called ...
-
CT scan or
MRI of the head
MRI of the head
A head MRI (magnetic resonance imaging) is an imaging test that uses powerful magnets and radio waves to create pictures of the brain and surrounding...
-
EEG
EEG
An electroencephalogram is a test to measure the electrical activity of the brain.
-
Lumbar puncture
Lumbar puncture
Cerebrospinal fluid (CSF) collection is a test to look at the fluid that surrounds the brain and spinal cord. CSF acts as a cushion, protecting the b...
Treatment depends on the cause of memory loss.
References
Kirshner HS, Ally B. Intellectual and memory impairments. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SK, eds. Bradley's Neurology in Clinical Practice . 7th ed. Philadelphia, PA: Elsevier; 2016:chap 7.
Oyebode F. Disturbance of memory. In: Oyebode F, ed. Sims' Symptoms in the Mind: Textbook of Descriptive Psychopathology . 5th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 5.
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Central nervous system - illustration
The central nervous system is comprised of the brain and spinal cord. The peripheral nervous system includes all peripheral nerves.
Central nervous system
illustration
-
Brain - illustration
The major areas of the brain have one or more specific functions.
Brain
illustration
-
Central nervous system - illustration
The central nervous system is comprised of the brain and spinal cord. The peripheral nervous system includes all peripheral nerves.
Central nervous system
illustration
-
Brain - illustration
The major areas of the brain have one or more specific functions.
Brain
illustration
-
Alzheimer disease
(Alt. Medicine)
Review Date: 1/5/2016
Reviewed By: Joseph V. Campellone, MD, Division of Neurology, Cooper University Hospital, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.