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Purpura

Blood spots; Skin hemorrhages

 

Purpura is purple-colored spots and patches that occur on the skin, and in mucus membranes, including the lining of the mouth.

Considerations

 

Purpura occurs when small blood vessels leak blood under the skin.

Purpura measure between 4 and 10 mm (millimeters) in diameter. When purpura spots are less than 4 mm in diameter, they are called petechiae . Purpura spots larger than 1 cm (centimeter) are called ecchymoses.

Platelets help the blood clot. A person with purpura may have normal platelet counts (non-thrombocytopenic purpuras) or low platelet counts (thrombocytopenic purpuras).

 

Causes

 

Non-thrombocytopenic purpuras may be due to:

  • Amyloidosis
  • Blood clotting disorders
  • Congenital cytomegalovirus
  • Congenital rubella syndrome
  • Drugs that affect platelet function
  • Fragile blood vessels seen in older people (senile purpura)
  • Hemangioma
  • Inflammation of the blood vessels (vasculitis), such as Henoch-Schönlein purpura , which causes a raised type of purpura
  • Pressure changes that occur during vaginal childbirth
  • Scurvy (vitamin C deficiency)
  • Steroid use
  • Certain infections
  • Injury

Thrombocytopenic purpura may be due to:

  • Drugs that reduce the platelet count
  • Idiopathic thrombocytopenic purpura (ITP)
  • Immune neonatal thrombocytopenia (can occur in infants whose mothers have ITP)
  • Meningococcemia , a raised type of purpura

 

When to Contact a Medical Professional

 

Call your health care provider for an appointment if you have signs of purpura.

 

What to Expect at Your Office Visit

 

The provider will examine your skin and ask about your medical history and symptoms, including:

  • Is this the first time you have had such spots?
  • When did they develop?
  • What color are they?
  • Do they look like bruises?
  • What medicines do you take?
  • What other medical problems have you had?
  • Does anyone in your family have similar spots?
  • What other symptoms do you have?

A skin biopsy may be done. Blood tests may be ordered to determine the cause of the purpura.

 

 

References

Marks JG, Miller JJ. Purpura. In: Marks JG, Miller JJ, eds. Lookingbill and Marks' Principles of Dermatology . 5th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 17.

 
  • Henoch-Schonlein purpura on the lower legs - illustration

    Henoch-Schonlein Purpura: This disorder usually presents with red to purple bumps on the legs, often accompanied by aching in the joints and fever. This condition follows an infection and usually resolves without treatment. Skin lesions most commonly occur below the knee but may also be seen on the thigh, buttocks, and rarely on the arms.

    Henoch-Schonlein purpura on the lower legs

    illustration

  • Henoch-Schonlein purpura on an infant's foot - illustration

    Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

    Henoch-Schonlein purpura on an infant's foot

    illustration

  • Henoch-Schonlein purpura on an infant's legs - illustration

    Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

    Henoch-Schonlein purpura on an infant's legs

    illustration

  • Henoch-Schonlein purpura on an infant's legs - illustration

    Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

    Henoch-Schonlein purpura on an infant's legs

    illustration

  • Henoch-Schonlein purpura on the legs - illustration

    Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

    Henoch-Schonlein purpura on the legs

    illustration

  • Meningococcemia on the calves - illustration

    Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) may occur. The tissue in areas may die (become necrotic or gangrenous). If the person survives, the areas heal with scarring.

    Meningococcemia on the calves

    illustration

  • Meningococcemia on the leg - illustration

    Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin (petechiae and purpura), and the tissue in these areas may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring. This picture demonstrates more hemorrhage and little tissue death.

    Meningococcemia on the leg

    illustration

  • Rocky mountain spotted fever on the foot - illustration

    Rocky Mountain spotted fever is caused by the organism Rickettsia rickettsii and is transmitted by a tick bite. It is a serious infection that produces a classical rash in about 90% of infected individuals. This is the typical appearance of the rash. There are many symptoms that affect the entire body (systemic).

    Rocky mountain spotted fever on the foot

    illustration

  • Meningococcemia associated purpura - illustration

    Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) typically occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.

    Meningococcemia associated purpura

    illustration

    • Henoch-Schonlein purpura on the lower legs - illustration

      Henoch-Schonlein Purpura: This disorder usually presents with red to purple bumps on the legs, often accompanied by aching in the joints and fever. This condition follows an infection and usually resolves without treatment. Skin lesions most commonly occur below the knee but may also be seen on the thigh, buttocks, and rarely on the arms.

      Henoch-Schonlein purpura on the lower legs

      illustration

    • Henoch-Schonlein purpura on an infant's foot - illustration

      Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

      Henoch-Schonlein purpura on an infant's foot

      illustration

    • Henoch-Schonlein purpura on an infant's legs - illustration

      Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

      Henoch-Schonlein purpura on an infant's legs

      illustration

    • Henoch-Schonlein purpura on an infant's legs - illustration

      Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

      Henoch-Schonlein purpura on an infant's legs

      illustration

    • Henoch-Schonlein purpura on the legs - illustration

      Henoch-Schonlein purpura is more commonly seen in children than adults and often occurs after an upper respiratory infection. It causes skin rashes that bleed into the skin (petechiae and purpura). Bleeding may also occur from the gastrointestinal tract and kidneys.

      Henoch-Schonlein purpura on the legs

      illustration

    • Meningococcemia on the calves - illustration

      Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) may occur. The tissue in areas may die (become necrotic or gangrenous). If the person survives, the areas heal with scarring.

      Meningococcemia on the calves

      illustration

    • Meningococcemia on the leg - illustration

      Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin (petechiae and purpura), and the tissue in these areas may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring. This picture demonstrates more hemorrhage and little tissue death.

      Meningococcemia on the leg

      illustration

    • Rocky mountain spotted fever on the foot - illustration

      Rocky Mountain spotted fever is caused by the organism Rickettsia rickettsii and is transmitted by a tick bite. It is a serious infection that produces a classical rash in about 90% of infected individuals. This is the typical appearance of the rash. There are many symptoms that affect the entire body (systemic).

      Rocky mountain spotted fever on the foot

      illustration

    • Meningococcemia associated purpura - illustration

      Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) typically occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.

      Meningococcemia associated purpura

      illustration

    A Closer Look

     

      Tests for Purpura

       

         

        Review Date: 4/14/2015

        Reviewed By: Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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