Antifreeze poisoning
Engine coolant poisoning
Antifreeze is a liquid used to cool engines. It is also called engine coolant. This article discusses poisoning caused by swallowing antifreeze.
This article is for information only. DO NOT use it to treat or manage an actual poison exposure. If you or someone you are with has an exposure, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Poisonous Ingredient
The poisonous ingredients in antifreeze are:
- Ethylene glycol
- Methanol
- Propylene glycol
Where Found
The above ingredients are found in various antifreezes. They may also be used in other products.
Symptoms
Below are symptoms of antifreeze poisoning in different parts of the body.
Airways and lungs
-
Rapid breathing
Rapid breathing
Hyperventilation is rapid and deep breathing. It is also called overbreathing, and it may leave you feeling breathless.
-
No breathing
No breathing
Most people take breathing for granted. People with certain illnesses may have breathing problems that they deal with on a regular basis. This arti...
Bladder and kidneys
-
Blood in urine
Blood in urine
Blood in your urine is called hematuria. The amount may be very small and only detected with urine tests or under a microscope. In other cases, the...
-
No urine output
or decreased urine output
No urine output
Decreased urine output means that you produce less urine than normal. Most adults make at least 500 ml of urine in 24 hours (a little over 2 cups)....
Eyes, ears, nose, and throat
-
Blurred vision
Blurred vision
There are many types of eye problems and vision disturbances, such as: HalosBlurred vision (the loss of sharpness of vision and the inability to see ...
- Blindness
Heart and blood
-
Rapid heartbeat
Rapid heartbeat
Palpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...
- Low blood pressure
Muscles and joints: Leg cramps
Leg cramps
Muscle cramps are when a muscle gets tight (contracts) without you trying to tighten it, and it does not relax. Cramps may involve all or part of on...
Nervous system
-
Coma
Coma
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
-
Convulsions
Convulsions
A seizure is the physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain. The term "seizure...
- Dizziness
-
Fatigue
Fatigue
Fatigue is a feeling of weariness, tiredness, or lack of energy.
- Headache
- Slurred speech
-
Stupor
(lack of alertness)
Stupor
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
-
Unconsciousness
Unconsciousness
Unconsciousness is when a person is unable to respond to people and activities. Doctors often call this a coma or being in a comatose state. Other c...
- Unsteady walk
- Weakness
Skin: Blue lips and fingernails
Blue lips and fingernails
Cyanosis is a bluish color to the skin or mucous membrane that is usually due to a lack of oxygen in the blood.
Stomach and gastrointestinal tract
- Nausea and vomiting
Home Care
Seek medical help right away. DO NOT make a person throw up unless poison control or a health care provider tells you to.
Use standard first aid and CPR for signs of shock or no heartbeat (cardiac arrest). Call your local poison control center or 911 for more help.
Before Calling Emergency
Have this information ready:
- Person's age, weight, and condition
- Name of product (as well as the ingredients, if known)
- Time it was swallowed
- Amount swallowed
Poison Control
Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. They will give you further instructions.
Poison Help hotline
For a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
Take the container with you to the hospital, if possible.
The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. The person may receive:
- Blood and urine tests
- Breathing support, including oxygen, tube through the mouth into the throat, and breathing machine
- Chest x-ray
- CT scan (advanced brain imaging)
- EKG (electrocardiogram or heart tracing)
- Intravenous fluids (through a vein)
- Medicines to reverse the effects of the poison
- Tube placed down the nose and into the stomach (sometimes)
Dialysis (kidney machine) treatment may be needed during recovery. Sometimes the person will need it for the rest of their life.
Outlook (Prognosis)
For ethylene glycol: Death may occur within the first 24 hours. If the patient survives, there may be little or no urine output for several weeks before the kidneys recover. Any brain damage may be permanent. Vision loss or blindness may also be permanent.
For methanol: Methanol is extremely toxic. As little as 2 tablespoons (1 ounce or 30 milliliters) can kill a child, and 4 to 16 tablespoons (2 to 8 ounces or 60 to 240 milliliters) can be deadly for an adult. The outcome depends on how much was swallowed and how soon appropriate care was given.
Permanent damage to the nervous system may occur. This can cause blindness, decreased mental functioning, and a condition similar to Parkinson disease.
References
Thomas SHL, White J. Poisoning. In: Walker BR, Colledge NR, Ralston SH, et al., eds. Davidson's Principles and Practice of Medicine . 22nd ed. Elsevier Churchill Livingstone; 2014:chap 9.
White SR. Toxic alcohols. In: Marx JA, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 155.
Review Date: 7/11/2015
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.