Ketoprofen overdose
Orudis overdose; Oruvail overdose
Ketoprofen is a nonsteroidal anti-inflammatory drug. It is used to treat pain, swelling, and inflammation. Ketoprofen overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.
This is for information only and not for use in the treatment or management of an actual overdose . DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Overdose
An overdose is when you take more than the normal or recommended amount of something, usually a drug. An overdose may result in serious, harmful sym...
Poisonous Ingredient
Ketoprofen can be harmful in large amounts.
Where Found
Ketoprofen is found in medicines with these names:
- Orudis
- Oruvail
Medicines with other names may also contain ketoprofen.
Symptoms
Below are symptoms of a ketoprofen overdose in different parts of the body.
EYES, EARS, NOSE, AND THROAT
-
Blurred vision
Blurred vision
There are many types of eye problems and vision disturbances, such as: HalosBlurred vision (the loss of sharpness of vision and the inability to see ...
-
Ringing in the ears
Ringing in the ears
Tinnitus is the medical term for "hearing" noises in your ears. It occurs when there is no outside source of the sounds. Tinnitus is often called "r...
HEART AND BLOOD
- Congestive heart failure (chest discomfort, shortness of breath, leg swelling)
-
High or
low blood pressure
Low blood pressure
Low blood pressure occurs when blood pressure is much lower than normal. This means the heart, brain, and other parts of the body do not get enough ...
STOMACH AND INTESTINES
- Diarrhea
- Nausea
- Possible loss of blood in the stomach and intestines
-
Stomach pain
Stomach pain
Abdominal pain is pain that you feel anywhere between your chest and groin. This is often referred to as the stomach region or belly.
- Vomiting (sometimes with blood)
LUNGS AND AIRWAYS
- Difficulty breathing
- Wheezing
NERVOUS SYSTEM
-
Headache
Headache
A headache is pain or discomfort in the head, scalp, or neck. Serious causes of headaches are rare. Most people with headaches can feel much better...
-
Agitation
Agitation
Agitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.
-
Coma
(decreased level of consciousness and lack of responsiveness)
Coma
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
-
Confusion
Confusion
Confusion is the inability to think as clearly or quickly as you normally do. You may feel disoriented and have difficulty paying attention, remembe...
-
Convulsions
Convulsions
A seizure is the physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain. The term "seizure...
-
Drowsiness
Drowsiness
Drowsiness refers to feeling abnormally sleepy during the day. People who are drowsy may fall asleep in inappropriate situations or at inappropriate...
- Fatigue and weakness
- Numbness and tingling
-
Seizures
Seizures
A seizure is the physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain. The term "seizure...
-
Unsteadiness
Unsteadiness
Walking abnormalities are unusual and uncontrollable walking patterns. They are usually due to diseases or injuries to the legs, feet, brain, spinal...
SKIN
- Blistering rash
- Bruising
- Sweating
Home Care
Seek medical help right away. Do NOT make the person throw up unless poison control or a health care provider tells you to.
Before Calling Emergency
Have this information ready:
- Person's age, weight, and condition
- Name of the product (and strength, if known)
- Time it was swallowed
- Amount swallowed
- If the medicine was prescribed for the person
Poison Control
Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.
Poison Help hotline
For a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
Take the container to the hospital with you, if possible.
The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.
The person may receive:
- Activated charcoal
- Blood and urine tests
- Breathing support, including a tube through the mouth into the lungs, and breathing machine (ventilator)
- EKG (electrocardiogram, or heart tracing)
- Chest x-ray
- Fluids through a vein (by IV)
- Laxative
- Medicine to to treat stomach inflammation and bleeding, breathing problems, and other symptoms
-
Tube through the mouth into the stomach to empty the stomach (
gastric lavage
)
Gastric lavage
Gastric suction is a procedure to empty the contents of your stomach.
Outlook (Prognosis)
How well someone does depends on the amount of ketoprofen they swallowed and how quickly they receive treatment. The faster someone gets medical help, the better the chance for recovery.
A mild overdose of ketoprofen does not usually cause serious problems. The person may have some stomach pain and vomiting (possibly with blood).
However, a large amount of internal bleeding is possible, and a blood transfusion may be needed. Passing a tube with a camera through the mouth into the stomach may be needed to stop the internal bleeding.
A large overdose can cause serious damage to children and adults. Death may occur.
References
Donovan JW. Nonsteroidal anti-inflammatory drugs. In: Shannon MW, Borron SW, Burns MJ, eds. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose . 4th ed. Philadelphia, PA: Elsevier Saunders; 2007:chap 51.
Long H. Acetaminophen, aspirin, and NSAIDs. In: Adams JG, ed. Emergency Medicine . 2nd ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 144.
Seger DL, Murray L. Aspirin and nonsteroidal agents. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 149.
Review Date: 10/13/2015
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.