Phencyclidine overdose
PCP overdose; Angel dust overdose; Sernyl overdose
Phencyclidine, or PCP, is an illegal street drug. It can cause hallucinations and severe agitation. This article discusses overdose due to PCP. An overdose is when someone takes more than the normal or recommended amount of something, usually a drug. An overdose may result in serious, harmful symptoms or death.
This is for information only and not for use in the treatment or management of an actual overdose. DO NOT use it to treat or manage an actual overdose . If you or someone you are with overdoses, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Overdose
An overdose is when you take more than the normal or recommended amount of something, usually a drug. An overdose may result in serious, harmful sym...
Symptoms
Symptoms of PCP overdose include:
-
Agitation
(overly excited, violent behavior)
Agitation
Agitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.
-
Altered state of consciousness
Altered state of consciousness
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
- Catatonic trance (person does not talk, move, or react)
-
Coma
Coma
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
-
Convulsions
Convulsions
A seizure is the physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain. The term "seizure...
- Hallucinations
- High blood pressure
-
Side-to-side eye movements
Side-to-side eye movements
Nystagmus is a term to describe fast, uncontrollable movements of the eyes that may be:Side to side (horizontal nystagmus)Up and down (vertical nysta...
- Psychosis
- Uncontrolled movement
-
Lack of coordination
Lack of coordination
Uncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...
People who have used PCP can be dangerous to themselves and others. DO NOT try to approach an agitated person who you think has used PCP.
Home Care
Seek medical help right away. DO NOT make the person throw up unless poison control or a health care provider tells you to.
Before Calling Emergency
Have this information ready:
- Person's age, weight, and condition
- Name of product (as well as the ingredients and strength if known)
- Time it was swallowed
- Amount swallowed
Poison Control
Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.
Local poison center
For a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
People being treated for PCP overdose may be sedated and placed in restraints to avoid hurting themselves or medical staff.
What to Expect at the Emergency Room
The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.
Additional treatment may include:
- Activated charcoal, if the drug has been taken by mouth
- Blood and urine tests
- Chest x-ray
- CT scan (advanced imaging) of the brain
- EKG (electrocardiogram, or heart tracing)
- Intravenous fluids (given through a vein)
- Medicines to treat symptoms
Outlook (Prognosis)
The outcome depends on several factors, including:
- The amount of PCP in the body
- The time between taking the drug and receiving treatment
Recovery from the psychotic state may take several weeks. The person should be in a quiet, darkened room. Long-term effects may include kidney failure and seizures. Repeated PCP use may cause long-term psychiatric problems.
Psychotic
Psychosis occurs when a person loses contact with reality. The person may: Have false beliefs about what is taking place, or who one is (delusions)S...
References
Hansen KN, Prybys KM. Hallucinogens. In: Tintinalli JE, Kelen GD, Stapczynski JS, Ma OJ, Cline DM, eds. Emergency Medicine: A Comprehensive Study Guide . 7th ed. New York, NY: McGraw-Hill; 2015:chap 182.
Ly TB, Williams SR. Hallucinogens. In: Marx JA, Hockberger RS, Walls RM, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 156.
Mycyk MB. Hallucinogens and drugs of abuse. In: Adams JG, ed. Emergency Medicine . 2nd ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 150.
Review Date: 7/6/2015
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.