Pentobarbital overdose
Nembutal overdose; Pentosol overdose; Sopental overdose; Repocal overdose
Pentobarbital is a sedative, which is a medicine that makes you sleepy. Pentobarbital overdose occurs when a person intentionally or accidentally takes too much of the medicine.
This is for information only and not for use in the treatment or management of an actual overdose. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Poisonous Ingredient
Pentobarbital
Where Found
Pentobarbital is the generic name for the following medicines:
- Nembutal
- Pentosol
- Repocal
- Sopental
Symptoms
Symptoms of a pentobarbital overdose may include:
-
Coma
Coma
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
-
Confusion
Confusion
Confusion is the inability to think as clearly or quickly as you normally do. You may feel disoriented and have difficulty paying attention, remembe...
- Decreased energy
-
Delirium
(confusion and agitation)
Delirium
Delirium is sudden severe confusion due to rapid changes in brain function that occur with physical or mental illness.
-
Difficulty breathing
Difficulty breathing
Breathing difficulty may involve:Difficult breathingUncomfortable breathingFeeling like you are not getting enough air
- Headache
- Large blisters
- Rash
- Sleepiness
- Slowed or stopped breathing
- Slurred speech
- Unsteady gait
Home Care
Seek immediate medical help. DO NOT make a person throw up unless told to do so by Poison Control or a health care professional.
Before Calling Emergency
Get the following information:
- The person's age, weight, and condition
- Name of product (as well as the ingredients and strength, if known)
- The time it was swallowed
- The amount swallowed
- If the medicine was prescribed for the person
However, DO NOT delay calling for help if this information is not immediately available.
Poison Control
Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This hotline number will let you talk to experts in poisoning. They will give you further instructions.
Local poison center
For a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...
This is a free and confidential service. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
The health care provider will measure and monitor vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The person may receive:
- Activated charcoal
- Airway support, including oxygen, breathing tube through the mouth (intubation), and breathing machine (ventilator)
- Blood and urine tests
- Chest x-ray
- EKG (electrocardiogram, or heart tracing)
- Fluids through a vein (IV)
- Laxative
- Medicines to treat symptoms
People who still have symptoms after 6 hours of treatment may need to be admitted to the hospital.
Outlook (Prognosis)
How well the person does depends on the amount of poison swallowed and how quickly treatment was received. With proper treatment, people can recover in 1 to 5 days. If the person was in a coma or in shock long-term (causing damage to many internal organs), a more serious outcome is possible.
References
Goldfrank LR, ed. Goldfrank's Toxicologic Emergencies . 8th ed. New York, NY: McGraw Hill; 2006.
Gussow L, Carlson A. Sedative hypnotics. In: Marx JA, Hockberger RS, Walls RM, et al, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 165.
Review Date: 1/16/2015
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.