Morphine overdose
Morphine is a very strong painkiller. Morphine overdose occurs when a person intentionally or accidentally takes too much of the medicine.
This article is for information only. Do NOT use it to treat or manage an actual poison exposure. If you or someone you are with has an exposure, call your local emergency number (such as 911), or your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Poisonous Ingredient
Morphine sulfate
Where Found
- Astramorph
- Morphine
- M S Contin
- Roxanol
Note: This list may not be all-inclusive.
Symptoms
Symptoms may include:
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Bluish-colored fingernails and lips
Bluish-colored fingernails and lips
Cyanosis is a bluish color to the skin or mucous membrane that is usually due to a lack of oxygen in the blood.
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Coma
Coma
Decreased alertness is a state of reduced awareness. A coma is a state of decreased alertness from which a person cannot be awakened. A long-term co...
- Constipation
-
Difficulty breathing
, shallow breathing, slow and
labored breathing
,
no breathing
Difficulty breathing
Breathing difficulty may involve:Difficult breathingUncomfortable breathingFeeling like you are not getting enough air
Labored breathing
Most people take breathing for granted. People with certain illnesses may have breathing problems that they deal with on a regular basis. This arti...
No breathing
Breathing that stops from any cause is called apnea. Slowed breathing is called bradypnea. Labored or difficult breathing is known as dyspnea....
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Drowsiness
Drowsiness
Drowsiness refers to feeling abnormally sleepy during the day. People who are drowsy may fall asleep in inappropriate situations or at inappropriate...
- Pinpoint pupils
- Nausea
- Possible seizures
- Spasms of the stomach or intestinal tract
- Vomiting
Home Care
Seek immediate medical help. DO NOT make a person throw up unless told to do so by Poison Control or a health care professional. Perform mouth-to-mouth breathing if the person stops breathing.
Mouth-to-mouth breathing
CPR stands for cardiopulmonary resuscitation. It is a lifesaving procedure that is done when someone's breathing or heartbeat has stopped. This may...
Before Calling Emergency
If possible, determine the following information:
- Person's age, weight, and condition (for example, is the person awake or alert?)
- Name of the product (ingredients and strengths, if known)
- Time it was swallowed
- Amount swallowed
However, DO NOT delay calling for help if this information is not immediately available.
Poison Control
Your local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This hotline number will let you talk to experts in poisoning. They will give you further instructions.
Local poison center
For a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...
This is a free and confidential service. You should call if you have any questions about poisoning or poison prevention. You can call 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The health care team will closely monitor the person's breathing. The person may receive:
- Activated charcoal
- Airway support, including oxygen, breathing tube through the mouth (intubation), and breathing machine (ventilator)
- Blood and urine tests
- Chest x-ray
- EKG (electrocardiogram, or heart tracing)
- Fluids through a vein (IV)
- Laxative
- Naloxone, a medicine (antidote) to reverse the effect of the poison, many doses may be needed
Outlook (Prognosis)
A large overdose can cause a person to stop breathing and die if medical attention or an antidote is not given right away. The person may need to be admitted to the hospital to continue treatment.
References
Bardsley CH. Opioids. In: Marx JA, Hockberger RS, Walls RM, et al. Rosen's Emergency Medicine: Concepts and Clinical Practice . 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 162.
Goldfrank LR, ed. Goldfrank's Toxicologic Emergencies . 9th ed. New York, NY: McGraw Hill; 2011.
Review Date: 1/16/2015
Reviewed By: Jacob L. Heller, MD, MHA, Emergency Medicine, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.