Epidural abscess
Abscess - epidural; Spinal abscess
An epidural abscess is a collection of pus (infected material) and germs between the outer covering of the brain and spinal cord and the bones of the skull or spine. The abscess causes swelling in the area.
Abscess
An abscess is a collection of pus in any part of the body. In most cases, the area around an abscess is swollen and inflamed.
Causes
Epidural abscess is a rare disorder caused by infection in the area between the bones of the skull, or spine, and the membranes covering the brain and spinal cord (meninges). This infection is called an intracranial epidural abscess if it is inside the skull area. It is called a spinal epidural abscess if it is found in the spine area. Most are located in the spine.
The spinal infection is usually caused by bacteria, but may be caused by a fungus. It can be due to other infections in the body (especially a urinary tract infection), or germs that spread through the blood. In some people, though, no other source of infection is found.
An abscess inside the skull is called an intracranial epidural abscess. The cause may be any of the following:
-
Chronic ear infections
Chronic ear infections
Chronic ear infection is fluid, swelling, or an infection behind the eardrum that does not go away or keeps coming back. It causes long-term or perm...
- Chronic sinusitis
- Head injury
-
Mastoiditis
Mastoiditis
Mastoiditis is an infection of the mastoid bone of the skull. The mastoid is located just behind the ear.
- Recent neurosurgery
An abscess of the spine is called a spinal epidural abscess. It may be seen in people with any of the following:
- Had back surgery or another invasive procedure involving the spine
- Bloodstream infections
-
Boils
, especially on the back or scalp
Boils
A boil is an infection that affects groups of hair follicles and nearby skin tissue. Related conditions include:CarbunculosisFolliculitis
- Bone infections of the spine (vertebral osteomyelitis)
People who inject drugs are also at increased risk.
Symptoms
Spinal epidural abscess may cause these symptoms:
-
Bowel
or
bladder incontinence
Bowel
Bowel incontinence is the loss of bowel control, causing you to pass stool unexpectedly. This can range from sometimes leaking a small amount of sto...
Bladder incontinence
Urinary (or bladder) incontinence happens when you are not able to keep urine from leaking out of your urethra. The urethra is the tube that carries...
- Difficulty urinating (urinary retention)
- Fever and back pain
Intracranial epidural abscess may cause these symptoms:
- Fever
- Headache
- Lethargy
- Nausea and vomiting
- Pain at the site of recent surgery that gets worse (especially if fever is present)
Nervous system symptoms depend on the location of the abscess and may include:
- Decreased ability to move any part of the body
-
Loss of sensation
in any area of the body, or abnormal changes in sensation
Loss of sensation
Numbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...
- Weakness
Exams and Tests
The health care provider will perform a physical exam to look for a loss of functions, such as movement or sensation.
Tests that may be done include:
-
Blood cultures
to check for bacteria in the blood
Blood cultures
A blood culture is a laboratory test to check for bacteria or other germs in a blood sample.
-
Complete blood count (
CBC
)
CBC
A complete blood count (CBC) test measures the following:The number of red blood cells (RBC count)The number of white blood cells (WBC count)The tota...
-
CT
scan of head or spine
CT
A computed tomography (CT) scan is an imaging method that uses x-rays to create pictures of cross-sections of the body. Related tests include:Abdomin...
- Draining of abscess and examination of the material
-
MRI
of head or spine
MRI
A magnetic resonance imaging (MRI) scan is an imaging test that uses powerful magnets and radio waves to create pictures of the body. It does not us...
-
Urine analysis and
culture
Culture
A urine culture is a lab test to check for bacteria or other germs in a urine sample. It can be used to check for a urinary tract infection in adults...
Treatment
The goal of treatment is to cure the infection and reduce the risk of permanent damage. Treatment usually includes antibiotics and surgery. In some cases, antibiotics alone are used.
Antibiotics are usually given through a vein (IV) for at least 4 to 6 weeks. Some people need to take them for a longer time, depending on the type of bacteria and how severe the disease is.
Surgery may be needed to drain or remove the abscess. Surgery is also often needed to reduce pressure on the spinal cord or brain, if there is weakness or damage to the nerves.
Outlook (Prognosis)
Early diagnosis and treatment greatly improves the chance of a good outcome. Once weakness, paralysis , or sensation changes occur, the chance of recovering lost function is greatly reduced. Permanent nervous system damage or death may occur.
Paralysis
Muscle function loss is when a muscle does not work or move normally. The medical term for complete loss of muscle function is paralysis.
Possible Complications
Complications may include:
-
Brain abscess
Brain abscess
A brain abscess is a collection of pus, immune cells, and other material in the brain, usually from a bacterial or fungal infection.
- Brain damage
- Bone infection (osteomyelitis)
- Chronic back pain
-
Meningitis
(infection of the membranes covering the brain and spinal cord)
Meningitis
Meningitis is an infection of the membranes covering the brain and spinal cord. This covering is called the meninges.
- Nerve damage
- Return of infection
-
Spinal cord abscess
Spinal cord abscess
Spinal cord abscess is the swelling and irritation (inflammation) and the collection of infected material (pus) and germs in or around the spinal cor...
When to Contact a Medical Professional
An epidural abscess is a medical emergency. Go to the emergency room or call the local emergency number (such as 911) if you have symptoms of spinal cord abscess.
Prevention
Treatment of certain infections, such as ear infections , sinusitis , and bloodstream infections, may decrease the risk of an epidural abscess. Early diagnosis and treatment are important to prevent complications.
Ear infections
Ear infections are one of the most common reasons parents take their children to the doctor. The most common type of ear infection is called otitis ...
Sinusitis
Sinusitis is present when the tissue lining the sinuses become swollen or inflamed. It occurs as the result of an infection from a virus, bacteria, ...
References
Kusuma S, Klineberg EO. Spinal infections: diagnosis and treatment of discitis, osteomyelitis, and epidural abscess. In: Steinmetz MP, Benzel EC, eds. Benzel's Spine Surgery . 4th ed. Philadelphia, PA: Elsevier; 2017:chap 122.
Tunkel AR. Subdural empyema, epidural abscess, and suppurative intracranial thrombophlebitis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Updated Edition . 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 93.
Review Date: 11/14/2016
Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.