Main Campus: Chesterfield, MO 63017 | 
Collagen vascular disease
In a class of diseases known as autoimmune disorders , the body's immune system attacks its own tissues. Some of these diseases are similar to each other such as arthritis and inflammation of arteries in the tissues. People who developed these disorders were previously said to have "connective tissue" or "collagen vascular" disease. We now have names for many of many specific conditions such as:
Autoimmune disorders
An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. There are more than 80 types of aut...
-
Ankylosing spondylitis
Ankylosing spondylitis
Ankylosing spondylitis (AS) is a chronic form of arthritis. It mostly affects the bones and joints at the base of the spine where it connects with t...
ImageRead Article Now Book Mark Article -
Dermatomyositis
Dermatomyositis
Dermatomyositis is a muscle disease that involves inflammation and a skin rash. It is a type of inflammatory myopathy.
ImageRead Article Now Book Mark Article -
Polyarteritis nodosa
Polyarteritis nodosa
Polyarteritis nodosa is a serious blood vessel disease. The small and medium-sized arteries become swollen and damaged.
ImageRead Article Now Book Mark Article -
Psoriatic arthritis
Psoriatic arthritis
Psoriatic arthritis is a joint problem (arthritis) that often occurs with a skin condition called psoriasis.
ImageRead Article Now Book Mark Article -
Rheumatoid arthritis
Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term disease. It leads to inflammation of the joints and surrounding tissues. It can also affect other organs....
ImageRead Article Now Book Mark Article -
Scleroderma
Scleroderma
Scleroderma is a disease that involves the buildup of scar-like tissue in the skin and elsewhere in the body. It also damages the cells that line th...
ImageRead Article Now Book Mark Article -
Systemic lupus erythematosus
Systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the body's immune system mistakenly attacks healthy tissue. It can af...
ImageRead Article Now Book Mark Article
When a specific disease cannot be diagnosed, more general terms may be used. These include as undifferentiated systemic rheumatic (connective tissue) diseases or overlap syndromes.
References
Bennett R. Overlap syndromes. In: Firestein GS, Budd RC, Harris ED Jr, et al, eds. Kelley's Textbook of Rheumatology . 9th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 86.
Mosca M, Tani C, Bornbardieri S. Undifferentiated connective tissue diseases (UCTD): a new frontier for rheumatology. Best Pract Res Clin Rheumatol . 2007;21(6):1011-23. PMID: 18068858 www.ncbi.nlm.nih.gov/pubmed/18068858 .
-
Dermatomyositis, heliotrope eyelids - illustration
This photograph demonstrates the sign "heliotrope eyelids" in which the eyelids develop a brown (violaceous - rather than red) color. Heliotrope eyelids and Gottron's papules on the knuckles are characteristic findings in dermatomyositis.
Dermatomyositis, heliotrope eyelids
illustration
-
Polyarteritis, microscopic on the shin - illustration
This is a picture of microscopic polyarteritis on the shin. The term polyarteritis means that many blood vessels are inflamed. These nodules are located just below the skin's surface (subcutaneous), are barely felt when pressing on the skin (palpable), and are tender. The skin is typically red (erythematous).
Polyarteritis, microscopic on the shin
illustration
-
Systemic lupus erythematosus rash on the face - illustration
This is a picture of a systemic lupus erythematosis rash on the face. Lupus erythematosis often produces a "butterfly rash" or malar rash. Typically, the rash also appears on the nose.
Systemic lupus erythematosus rash on the face
illustration
-
Sclerodactyly - illustration
The most classic symptom of scleroderma is a type of skin tightening called sclerodactyly. The initial stages of the disease involves swelling of the fingers. Later, as the connective tissue becomes fibrotic, skin on the fingers and toes becomes hard and shiny. The fingers can become difficult to bend and can form contractures due to the severe tightening of the skin.
Sclerodactyly
illustration
-
Rheumatoid arthritis - illustration
The affect of rheumatoid arthritis can progress to the degree that it is crippling. Deformities distinctive to late-stage rheumatoid arthritis such as ulnar deviation of the bones of the hands, or swan-neck deviation of the fingers occur because muscles and tendons on one side of the joint may overpower those on the other side, pulling the bones out of alignment.
Rheumatoid arthritis
illustration
-
Dermatomyositis, heliotrope eyelids - illustration
This photograph demonstrates the sign "heliotrope eyelids" in which the eyelids develop a brown (violaceous - rather than red) color. Heliotrope eyelids and Gottron's papules on the knuckles are characteristic findings in dermatomyositis.
Dermatomyositis, heliotrope eyelids
illustration
-
Polyarteritis, microscopic on the shin - illustration
This is a picture of microscopic polyarteritis on the shin. The term polyarteritis means that many blood vessels are inflamed. These nodules are located just below the skin's surface (subcutaneous), are barely felt when pressing on the skin (palpable), and are tender. The skin is typically red (erythematous).
Polyarteritis, microscopic on the shin
illustration
-
Systemic lupus erythematosus rash on the face - illustration
This is a picture of a systemic lupus erythematosis rash on the face. Lupus erythematosis often produces a "butterfly rash" or malar rash. Typically, the rash also appears on the nose.
Systemic lupus erythematosus rash on the face
illustration
-
Sclerodactyly - illustration
The most classic symptom of scleroderma is a type of skin tightening called sclerodactyly. The initial stages of the disease involves swelling of the fingers. Later, as the connective tissue becomes fibrotic, skin on the fingers and toes becomes hard and shiny. The fingers can become difficult to bend and can form contractures due to the severe tightening of the skin.
Sclerodactyly
illustration
-
Rheumatoid arthritis - illustration
The affect of rheumatoid arthritis can progress to the degree that it is crippling. Deformities distinctive to late-stage rheumatoid arthritis such as ulnar deviation of the bones of the hands, or swan-neck deviation of the fingers occur because muscles and tendons on one side of the joint may overpower those on the other side, pulling the bones out of alignment.
Rheumatoid arthritis
illustration
-
Periodontal disease
(In-Depth)
Review Date: 1/20/2015
Reviewed By: Gordon A. Starkebaum, MD, professor of medicine, division of rheumatology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
