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Gumma

 

A gumma is a soft, tumor-like growth of the tissues (granuloma) that occurs in people with syphilis.

Causes

A gumma is caused by the bacteria that causes syphilis . It appears during late-stage tertiary syphilis. It most often contains a mass of dead and swollen fiber-like tissue. It is most often seen in the liver. It also can occur in the:

  • Bone
  • Brain
  • Heart
  • Skin
  • Testis
  • Eyes

Similar-looking sores sometimes occur with tuberculosis .

 

References

Eckert LO, Lentz GM. Infections of the lower genital tract: Vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. In: Lentz GM, Lobo RA, Gershenson DM, Katz VL, eds. Comprehensive Gynecology . 6th ed. Philadelphia, PA: Elsevier Mosby; 2012:chap 23.

Radolf JD, Tramont EC, Salazar JC. Syphilis ( Treponema pallidum ). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases . 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 239.

Workowski KA, Bolan GA; Centers for Disease Control and Prevention (CDC). Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep . 2015;64(RR-03):1-137. PMID: 26042815 www.ncbi.nlm.nih.gov/pubmed/26042815 .

 
  • Male and female reproductive systems - illustration

    The male and female reproductive systems, viewed from a mid-sagittal section.

    Male and female reproductive systems

    illustration

    • Male and female reproductive systems - illustration

      The male and female reproductive systems, viewed from a mid-sagittal section.

      Male and female reproductive systems

      illustration


     

    Review Date: 9/26/2015

    Reviewed By: Daniel N. Sacks MD, FACOG, obstetrics & gynecology in private practice, West Palm Beach, FL. Review Provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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