Cellulitis
Skin infection - bacterial
Cellulitis is a common skin infection caused by bacteria. It affects the middle layer of the skin (dermis) and the tissues below. Sometimes, muscle can be affected.
Causes
Staphylococcus and streptococcus bacteria are the most common causes of cellulitis.
Normal skin has many types of bacteria living on it. When there is a break in the skin, these bacteria can cause a skin infection.
Risk factors for cellulitis include:
- Cracks or peeling skin between the toes
-
History of
peripheral vascular disease
Peripheral vascular disease
Peripheral artery disease (PAD) is a condition of the blood vessels that supply the legs and feet. It leads to narrowing and hardening of the arteri...
- Injury or trauma with a break in the skin (skin wounds)
-
Insect bites and stings
, animal bites, or human bites
Insect bites and stings
Insect bites and stings can cause an immediate skin reaction. The bite from fire ants and the sting from bees, wasps, and hornets are most often pai...
-
Ulcers
from certain diseases, including diabetes and vascular disease
Ulcers
An ulcer is a crater-like sore on the skin or mucous membrane. Ulcers form when the top layers of skin or tissue have been removed. They can occur ...
- Use of corticosteroid medications or medications that suppress the immune system
- Wound from a recent surgery
Symptoms
Symptoms of cellulitis include:
-
Fever
Fever
Fever is the temporary increase in the body's temperature in response to a disease or illness. A child has a fever when the temperature is at or abov...
- Pain or tenderness in the affected area
-
Skin redness or inflammation
that gets bigger as the infection spreads
Skin redness or inflammation
Rashes involve changes in the color, feeling or texture of your skin.
- Skin sore or rash that starts suddenly, and grows quickly in the first 24 hours
- Tight, glossy, stretched appearance of the skin
- Warm skin in the area of redness
- Joint stiffness from swelling of the tissue over the joint
- Hair loss at the site of the infection
- Nausea and vomiting
Signs of infection include any of the following:
- Chills or shaking
- Fatigue
- General ill feeling
-
Muscle aches
and pains
Muscle aches
Muscle aches and pains are common and can involve more than 1 muscle. Muscle pain also can involve ligaments, tendons, and fascia. Fascia are the s...
- Warm skin
- Sweating
Exams and Tests
The health care provider will perform a physical exam. This may reveal:
- Redness, warmth, and swelling of the skin
- Possible drainage, if there is a buildup of pus ( abscess ) with the skin infection
-
Swollen glands
(lymph nodes) near the affected area
Swollen glands
Lymph nodes are present throughout your body. They are an important part of your immune system. Lymph nodes help your body recognize and fight germ...
The provider may mark the edges of the redness with a pen, to see if the redness goes past the marked border over the next several days.
Tests that may be ordered include:
-
Blood culture
Blood culture
A blood culture is a laboratory test to check for bacteria or other germs in a blood sample.
-
Complete blood count (
CBC
)
CBC
A complete blood count (CBC) test measures the following:The number of red blood cells (RBC count)The number of white blood cells (WBC count)The tota...
- Culture of any fluid or material inside the affected area
-
A
biopsy
may be done if other conditions are suspected
Biopsy
A skin lesion biopsy is when a small amount of skin is removed so it can be examined. The skin is tested to look for skin conditions or diseases. A...
Treatment
You will likely be prescribed antibiotics to be taken by mouth. You may be given pain medicine as well, if needed.
At home, raise the infected area higher than your heart to reduce swelling. Rest until your symptoms improve.
You may need to stay in a hospital if:
- You are very sick (for example, you have a very high temperature, blood pressure problems, or nausea and vomiting that does not go away)
- You have been on antibiotics and the infection is getting worse (spreading beyond the original pen marking)
- Your immune system is not working well (due to cancer, HIV)
- You have an infection around your eyes
- You require antibiotics through a vein (IV)
Outlook (Prognosis)
Cellulitis usually goes away after taking antibiotics for 7 to 10 days. Longer treatment may be needed if cellulitis is more severe. This may occur if you have a chronic disease or your immune system is not working properly.
People with fungal infections of the feet may have cellulitis that keeps coming back. Cracks in the skin from the fungal infection allow the bacteria to get into the skin.
Possible Complications
The following may result if cellulitis isn't treated or treatment doesn't work:
- Blood infection (sepsis)
-
Bone infection (
osteomyelitis
)
Osteomyelitis
Osteomyelitis is a bone infection. It is mainly caused by bacteria or other germs.
-
Inflammation of the lymph vessels (
lymphangitis
)
Lymphangitis
Lymphadenitis is an infection of the lymph nodes (also called lymph glands). It is a common complication of certain bacterial infections.
- Inflammation of the heart (endocarditis)
-
Meningitis
Meningitis
Meningitis is an infection of the membranes covering the brain and spinal cord. This covering is called the meninges.
-
Shock
Shock
Shock is a life-threatening condition that occurs when the body is not getting enough blood flow. Lack of blood flow means that the cells and organs...
- Tissue death ( gangrene )
When to Contact a Medical Professional
Call your provider if:
- You have symptoms of cellulitis
-
You are being treated for cellulitis and you develop new symptoms, such as persistent fever, drowsiness,
lethargy
, blistering over the cellulitis, or red streaks that spread
Lethargy
Fatigue is a feeling of weariness, tiredness, or lack of energy.
Seek medical attention right away if the cellulitis is on your face.
Prevention
Protect your skin by:
- Keeping your skin moist with lotions or ointments to prevent cracking
- Wearing shoes that fit well and provide enough room for your feet
- Learning how to trim your nails to avoid harming the skin around them
- Wearing appropriate protective equipment when participating in work or sports
Whenever you have a break in the skin:
- Clean the break carefully with soap and water. Apply an antibiotic cream or ointment every day.
- Cover with a bandage and change it every day until a scab forms.
- Watch for redness, pain, drainage, or other signs of infection.
References
Heagerty AHM. Cellulitis and erysipelas. In: Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 39.
Pasternak MS, Swartz MN. Cellulitis, necrotizing fasciitis, and subcutaneous tissue infections. In: Bennett JE, Dolin R, Blaser MJ, eds.
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases.
8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 95.
-
Cellulitis - illustration
Cellulitis is a deep infection of the skin, usually accompanied by generalized (systemic) symptoms such as fever and chills. The area of redness increases in size as the infection spreads. The center of the circled lesion has been biopsied.
Cellulitis
illustration
-
Cellulitis on the arm - illustration
Cellulitis is a noncontagious inflammation of the connective tissue of the skin, resulting from a bacterial infection. Antibiotics are given to control infection, and analgesics may be needed to control pain. Within 7 to 10 days of treatment cellulitis can be cured.
Cellulitis on the arm
illustration
-
Cellulitis - illustration
Cellulitis is a deep infection of the skin, usually accompanied by generalized (systemic) symptoms such as fever and chills. The area of redness increases in size as the infection spreads. The center of the circled lesion has been biopsied.
Cellulitis
illustration
-
Cellulitis on the arm - illustration
Cellulitis is a noncontagious inflammation of the connective tissue of the skin, resulting from a bacterial infection. Antibiotics are given to control infection, and analgesics may be needed to control pain. Within 7 to 10 days of treatment cellulitis can be cured.
Cellulitis on the arm
illustration
Review Date: 4/14/2015
Reviewed By: Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.