Renal vein thrombosis
Blood clot in the renal vein; Occlusion - renal vein
Renal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney.
Blood clot
Blood clots are clumps that occur when blood hardens from a liquid to a solid. A blood clot that forms inside one of your veins or arteries is calle...
Causes
Renal vein thrombosis is an uncommon disorder. It may be caused by:
-
Abdominal aortic aneurysm
Abdominal aortic aneurysm
The aorta is the main blood vessel that supplies blood to the abdomen, pelvis, and legs. An abdominal aortic aneurysm occurs when an area of the aor...
- Hypercoaguable state: clotting disorders
-
Dehydration
(mostly in infants)
Dehydration
Dehydration occurs when your body does not have as much water and fluids as it should. Dehydration can be mild, moderate, or severe, based on how muc...
- Estrogen use
-
Nephrotic syndrome
Nephrotic syndrome
Nephrotic syndrome is a group of symptoms that include protein in the urine, low blood protein levels in the blood, high cholesterol levels, high tri...
- Pregnancy
-
Scar formation with pressure on the
renal
vein
Renal
The term "renal" refers to the kidney. For example, renal failure means kidney failure. Related topics:Kidney diseaseKidney disease - dietKidney fai...
- Trauma (to the back or abdomen)
-
Tumor
Tumor
A tumor is an abnormal growth of body tissue. Tumors can be cancerous (malignant) or noncancerous (benign).
In adults, the most common cause is nephrotic syndrome. In infants, the most common cause is dehydration.
Symptoms
Symptoms may include:
- Blood clot to the lung
- Bloody urine
-
Decreased urine output
Decreased urine output
Decreased urine output means that you produce less urine than normal. Most adults make at least 500 ml of urine in 24 hours (a little over 2 cups)....
-
Flank pain
or low back pain
Flank pain
Flank pain is pain in one side of the body between the upper belly area (abdomen) and the back.
Exams and Tests
An exam may not reveal the specific problem. However, it may indicate nephrotic syndrome or other causes of renal vein thrombosis.
Tests include:
-
Abdominal CT scan
Abdominal CT scan
An abdominal CT scan is an imaging method. This test uses x-rays to create cross-sectional pictures of the belly area. CT stands for computed tomog...
-
Abdominal MRI
Abdominal MRI
An abdominal magnetic resonance imaging scan is an imaging test that uses powerful magnets and radio waves. The waves create pictures of the inside ...
-
Abdominal ultrasound
Abdominal ultrasound
Abdominal ultrasound is a type of imaging test. It is used to look at organs in the abdomen, including the liver, gallbladder, spleen, pancreas, and...
- Duplex Doppler exam of the renal veins
-
Urinalysis
may show
protein in the urine
or
red blood cells in the urine
Urinalysis
Urinalysis is the physical, chemical, and microscopic examination of urine. It involves a number of tests to detect and measure various compounds th...
Protein in the urine
The protein urine dipstick test measures the presence of proteins, such as albumin, in a urine sample. Albumin and protein can also be measured using...
Red blood cells in the urine
The RBC urine test measures the number of red blood cells in a urine sample.
- X-ray of the kidney veins (venography)
Treatment
The treatment is focused on preventing new clot formations and reducing the risk of the clot traveling to other locations in the body (embolization).
You may get medicines that prevent blood clotting (anticoagulants). You may be told to rest in bed or cut down on activity for a short time.
If sudden kidney failure develops, you may need dialysis for a short period.
Dialysis
Dialysis treats end-stage kidney failure. It removes harmful substances from the blood when the kidneys cannot. This article focuses on peritoneal d...
Outlook (Prognosis)
Renal vein thrombosis most often gets better over time without lasting damage to the kidneys.
Possible Complications
Complications may include:
- Acute renal failure (especially if thrombosis occurs in a dehydrated child)
- End stage renal disease
-
Blood clot moves to the lungs (
pulmonary embolism
)
Pulmonary embolism
A pulmonary embolus is a blockage of an artery in the lungs. The most common cause of the blockage is a blood clot.
- Formation of new blood clots
When to Contact a Medical Professional
Call your health care provider if you have symptoms of renal vein thrombosis.
If you have experienced renal vein thrombosis, call your provider if you have:
- Decrease in urine output
-
Breathing problems
Breathing problems
Breathing difficulty may involve:Difficult breathingUncomfortable breathingFeeling like you are not getting enough air
- Other new symptoms
Prevention
In most cases, there is no specific way to prevent renal vein thrombosis. Keeping enough fluids in the body may help reduce risk.
Aspirin is sometimes used to prevent renal vein thrombosis in people who have had a kidney transplant. Blood thinners such as warfarin may be recommended for some people with chronic kidney disease.
References
DuBose TD Jr, Santos RM. Vascular disorders of the kidney In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 125.
Ruggenenti P, Cravede P, Remuzzi G. Microvascular and macrovascular diseases of the kidney. In: Taal MW, Chertow GM, Marsden PA, et al, eds. Brenner and Rector's The Kidney . 9th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 34.
-
Kidney anatomy - illustration
The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and stimulating red blood cell production.
Kidney anatomy
illustration
-
Kidney - blood and urine flow - illustration
This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow.
Kidney - blood and urine flow
illustration
-
Kidney anatomy - illustration
The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and stimulating red blood cell production.
Kidney anatomy
illustration
-
Kidney - blood and urine flow - illustration
This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow.
Kidney - blood and urine flow
illustration
Review Date: 5/19/2015
Reviewed By: Charles Silberberg, DO, private practice specializing in nephrology, affiliated with New York Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.