Ascites
Portal hypertension - ascites; Cirrhosis - ascites; Liver failure - ascites; Alcohol use - ascites; End-stage liver disease - ascites; ESLD - ascites
Ascites is the build-up of fluid in the space between the lining of the abdomen and abdominal organs.
Causes
Ascites results from high pressure in the blood vessels of the liver (portal hypertension) and low levels of a protein called albumin .
Albumin
Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood. Albumin c...
Diseases that can cause severe liver damage can lead to ascites. These include long-term hepatitis C or B infection and alcohol abuse over many years.
Severe liver damage
Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood. Albumin c...
Hepatitis C or B infection
Hepatitis is swelling and inflammation of the liver.
Alcohol abuse
Alcoholic liver disease is damage to the liver and its function due to alcohol abuse.
People with certain cancers in the abdomen may develop ascites. These include cancer of the appendix, colon, ovaries, uterus, pancreas, and liver.
Other conditions that can cause this problem include:
- Clots in the veins of the liver (portal vein thrombosis)
-
Congestive heart failure
Congestive heart failure
Heart failure is a condition in which the heart is no longer able to pump oxygen-rich blood to the rest of the body efficiently. This causes symptom...
- Pancreatitis
- Thickening and scarring of the sac-like covering of the heart
Kidney dialysis may also be linked to ascites.
Symptoms
Symptoms may develop slowly or suddenly depending on the cause of ascites. You may have no symptoms if there is only a small amount of fluid in the belly.
As more fluid collects, you may have abdominal pain and bloating. Large amounts of fluid can cause shortness of breath.
Many other symptoms of liver failure may also be present.
Liver failure
Cirrhosis is scarring of the liver and poor liver function. It is the last stage of chronic liver disease.
Exams and Tests
Your doctor will do a physical exam to determine the amount of swelling in your belly.
You may also have the following tests to assess your liver and kidneys:
-
24-hour urine collection
24-hour urine collection
24-hour urine protein measures the amount of protein released in urine over a 24-hour period.
- Electrolyte levels
- Kidney function tests
- Liver function tests
- Tests to measure the risk of bleeding and protein levels in the blood
- Urinalysis
- Abdominal ultrasound
Your doctor may also use a thin needle to withdraw ascites fluid from your belly. The fluid is tested to look for the cause of ascites.
Use a thin needle
Liver transplant is surgery to replace a diseased liver with a healthy liver.
Treatment
LIFESTYLE CHANGES
The condition that causes ascites will be treated, if possible.
Treatments for fluid build-up may include lifestyle changes :
Lifestyle changes
You have cirrhosis of the liver. Scar tissue forms and your liver gets smaller and harder. Most of the time, this damage cannot be undone. However...
- Avoiding alcohol
- Lowering salt in your diet (no more than 1,500 mg/day of sodium)
- Limiting fluid intake
You may also get medicines from your doctor, including:
- "Water pills" (diuretics) to get rid of extra fluid
- Antibiotics for infections
Other things you can do to help take care of your liver disease are:
- Get vaccinated for diseases such as influenza, hepatitis A and hepatitis B, and pneumococcal pneumonia
- Talk to your doctor about all medicines you take, including herbs and supplements and over-the-counter medicines
Procedures that you may have are:
- Inserting a needle into the belly to remove large volumes of fluid (called a paracentesis)
-
Placing a
special tube or shunt
inside your liver (TIPS) to repair blood flow to the liver
Special tube or shunt
Transjugular intrahepatic portosystemic shunt (TIPS) is a procedure to create new connections between two blood vessels in your liver. You may need ...
People with end-stage liver disease may need a liver transplant .
Liver transplant
Liver transplant is surgery to replace a diseased liver with a healthy liver.
Possible Complications
Complications may include:
-
Spontaneous bacterial peritonitis
(a life-threatening infection of the ascites fluid)
Spontaneous bacterial peritonitis
The peritoneum is the thin tissue that lines the inner wall of the abdomen and covers most of the organs. Peritonitis is present when this tissue be...
-
Hepatorenal syndrome
(kidney failure)
Hepatorenal syndrome
Hepatorenal syndrome is a condition in which there is progressive kidney failure. It occurs in a person with cirrhosis of the liver. It is a seriou...
- Weight loss and protein malnutrition
- Mental confusion, change in the level of alertness, or coma (hepatic encephalopathy)
- Other complications of liver cirrhosis
When to Contact a Medical Professional
If you have ascites, call your health care provider right away if you have:
- Fever above 100.5°F (38.05°C), or a fever that does not go away
- Belly pain
- Blood in your stool or black, tarry stools
- Blood in your vomit
- Bruising or bleeding that occurs easily
- Build-up of fluid in your belly
- Swollen legs or ankles
- Breathing problems
- Confusion or problems staying awake
- Yellow color in your skin and the whites of your eyes (jaundice)
References
Garcia-Tsao G. Cirrhosis and its sequelae. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 153.
Runyon BA. Ascites and spontaneous bacterial peritonitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease . 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 93.
Runyon BA; AASLD Practice Guidelines Committee. Management of adult patients with ascites due to cirrhosis: update 2012. Hepatology . 2009;49(6):2087-2107. PMID: 19475696 www.ncbi.nlm.nih.gov/pubmed/19475696 .
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Ascites with ovarian cancer, CT scan - illustration
This CT scan of the lower abdomen shows a massive amount of free abdominal fluid (ascites) in a patient with ovarian cancer.
Ascites with ovarian cancer, CT scan
illustration
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Digestive system organs - illustration
The digestive system organs in the abdominal cavity include the liver, gallbladder, stomach, small intestine and large intestine.
Digestive system organs
illustration
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Ascites with ovarian cancer, CT scan - illustration
This CT scan of the lower abdomen shows a massive amount of free abdominal fluid (ascites) in a patient with ovarian cancer.
Ascites with ovarian cancer, CT scan
illustration
-
Digestive system organs - illustration
The digestive system organs in the abdominal cavity include the liver, gallbladder, stomach, small intestine and large intestine.
Digestive system organs
illustration
Review Date: 8/14/2015
Reviewed By: Subodh K. Lal, MD, gastroenterologist at Gastrointestinal Specialists of Georgia, Austell, GA. Review provided by VeriMed Healthcare Network. Internal review and update on 09/01/2016 by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.