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Peripartum cardiomyopathy

Cardiomyopathy - peripartum; Cardiomyopathy - pregnancy

 

Peripartum cardiomyopathy is a rare disorder in which a pregnant woman's heart becomes weakened and enlarged. It develops during the last month of pregnancy, or within 5 months after the baby is born.

Causes

 

Cardiomyopathy occurs when there is damage to the heart. As a result, the heart muscle becomes weak and does not pump well. This affects the lungs, liver, and other body systems.

Peripartum cardiomyopathy is a form of dilated cardiomyopathy in which no other cause of heart weakening can be found.

It may occur in childbearing women of any age, but it is most common after age 30.

Risk factors for the condition include:

  • Obesity
  • Personal history of cardiac disorders such as myocarditis
  • Use of certain medicines
  • Smoking
  • Alcoholism
  • Multiple pregnancies
  • Old age
  • Pre-ecclampsia
  • African American descent
  • Poor nourishment

 

Symptoms

 

Symptoms may include:

  • Fatigue
  • Feeling of heart racing or skipping beats (palpitations)
  • Increased nighttime urination (nocturia)
  • Shortness of breath with activity and when lying flat
  • Swelling of the ankles

 

Exams and Tests

 

During a physical exam, the health care provider will look for signs of fluid in the lungs by touching and tapping with the fingers. A stethoscope will be used to listen for lung crackles, a rapid heart rate, or abnormal heart sounds.

The liver may be enlarged and neck veins may be swollen. Blood pressure may be low or may drop when standing up.

Heart enlargement, congestion of the lungs or the veins in the lungs, decreased cardiac output, decreased movement or functioning of the heart, or heart failure may show up on:

  • Chest x-ray
  • Chest CT scan
  • Coronary angiography
  • Echocardiogram
  • Nuclear heart scan
  • Cardiac MRI

A heart biopsy may help determine if the underlying cause of cardiomyopathy is a heart muscle infection (myocarditis). However, this procedure is not done very often.

 

Treatment

 

A woman may need to stay in the hospital until acute symptoms subside.

Because it is very often possible to restore heart function, and the women who have this condition are often young and otherwise healthy, care is often aggressive.

When severe symptoms occur, this may include extreme steps such as:

  • Use of an assistive heart pump (aortic counterpulsation balloon, left ventricular assist device)
  • Immunosuppressive therapy (such as medicines used to treat cancer or prevent rejection of a transplanted organ)
  • Heart transplant if severe congestive heart failure persists

For most women, however, treatment mainly focuses on relieving the symptoms. Some symptoms go away on their own without treatment.

Medicines that are often used include:

  • Digitalis to strengthen the heart's pumping ability
  • Diuretics ("water pills") to remove excess fluid
  • Low-dose beta-blockers
  • Other blood pressure medicines

A low-salt diet may be recommended. Fluid may be restricted in some cases. Activities, including nursing the baby, may be limited when symptoms develop.

Daily weighing may be recommended. A weight gain of 3 to 4 pounds (1.5 to 2 kilograms) or more over 1 or 2 days may be a sign of fluid buildup.

Women who smoke and drink alcohol will be advised to stop, since these habits may make the symptoms worse.

 

Outlook (Prognosis)

 

There are several possible outcomes in peripartum cardiomyopathy. Some women remain stable for long periods, while others get worse slowly.

Others get worse very quickly and may be candidates for a heart transplant. About 4% of people will require heart transplantation and 9% may die suddenly or die from complications of the procedure.

The outlook is good when a woman's heart returns to normal after the baby is born. If the heart remains abnormal, future pregnancies may result in heart failure. It is not known how to predict who will recover and who will develop severe heart failure. Up to about one half of women will recover completely.

Women who develop peripartum cardiomyopathy are at high risk of developing the same problem with future pregnancies. The rate of recurrence is about 30%. Therefore, women who have had this condition should discuss birth control methods with their provider.

 

Possible Complications

 

Complications include:

  • Cardiac arrhythmias (can be deadly)
  • Congestive heart failure
  • Clot formation in the heart which can embolize (travel to other parts of the body)

 

When to Contact a Medical Professional

 

Call your provider if you are currently pregnant or have recently delivered a baby and think you may have signs of cardiomyopathy.

Get medical help right away if you develop chest pain, palpitations, faintness, or other new or unexplained symptoms.

 

Prevention

 

Eat a well-balanced diet and get regular exercise to help keep your heart strong. Avoid cigarettes and alcohol. Your provider may advise you to avoid getting pregnant again if you have had heart failure during a previous pregnancy.

 

 

Open References

References

McKenna W, Elliott P. Diseases of the myocardium and endocardium. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 60.

Warnes CA. Pregnancy and heart disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine . 10th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 78.

 
  • Heart, section through the middle

    Heart, section through the middle - illustration

    The interior of the heart is composed of valves, chambers, and associated vessels.

    Heart, section through the middle

    illustration

  • Heart, front view

    Heart, front view - illustration

    The external structures of the heart include the ventricles, atria, arteries and veins. Arteries carry blood away from the heart while veins carry blood into the heart. The vessels colored blue indicate the transport of blood with relatively low content of oxygen and high content of carbon dioxide. The vessels colored red indicate the transport of blood with relatively high content of oxygen and low content of carbon dioxide.

    Heart, front view

    illustration

  • Peripartum cardiomyopathy

    Peripartum cardiomyopathy - illustration

    Peripartum cardiomyopathy is a rare disorder in which a weakened heart is diagnosed within the last month of pregnancy or within 5 months after delivery, without other identifiable causes for dysfunction of the heart. The heart muscle becomes enlarged and weakened and cannot pump blood efficiently. Decreased heart function affects the lungs, liver, and other body systems.

    Peripartum cardiomyopathy

    illustration

    • Heart, section through the middle

      Heart, section through the middle - illustration

      The interior of the heart is composed of valves, chambers, and associated vessels.

      Heart, section through the middle

      illustration

    • Heart, front view

      Heart, front view - illustration

      The external structures of the heart include the ventricles, atria, arteries and veins. Arteries carry blood away from the heart while veins carry blood into the heart. The vessels colored blue indicate the transport of blood with relatively low content of oxygen and high content of carbon dioxide. The vessels colored red indicate the transport of blood with relatively high content of oxygen and low content of carbon dioxide.

      Heart, front view

      illustration

    • Peripartum cardiomyopathy

      Peripartum cardiomyopathy - illustration

      Peripartum cardiomyopathy is a rare disorder in which a weakened heart is diagnosed within the last month of pregnancy or within 5 months after delivery, without other identifiable causes for dysfunction of the heart. The heart muscle becomes enlarged and weakened and cannot pump blood efficiently. Decreased heart function affects the lungs, liver, and other body systems.

      Peripartum cardiomyopathy

      illustration

    A Closer Look

     

      Self Care

       

        Tests for Peripartum cardiomyopathy

         
         

        Review Date: 5/5/2016

        Reviewed By: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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