Lung metastases
Metastases to the lung; Metastatic cancer to the lung; Lung cancer - metastases
Lung metastases are cancerous tumors that start somewhere else in the body and spread to the lungs.
Causes
Metastatic tumors in the lungs are cancers that developed at other places in the body (or other parts of the lungs). They then spread through the bloodstream or lymphatic system to the lungs. It is different than lung cancer that starts in the lungs.
Nearly any cancer can spread to the lungs. Common cancers include:
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Bladder cancer
Bladder cancer
Bladder cancer is a cancer that starts in the bladder. The bladder is the body part that holds and releases urine. It is in the center of the lower...
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Breast cancer
Breast cancer
Breast cancer is cancer that starts in the tissues of the breast. There are 2 main types of breast cancer:Ductal carcinoma starts in the tubes (duct...
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Colon cancer
Colon cancer
Colon, or colorectal cancer, is cancer that starts in the large intestine (colon) or the rectum (end of the colon). Other types of cancer can affect ...
- Kidney cancer
- Melanoma
- Ovarian cancer
- Sarcoma
- Thyroid cancer
Symptoms
Symptoms may include any of the following:
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Bloody sputum
Bloody sputum
Coughing up blood is the spitting up of blood or bloody mucus from the lungs and throat (respiratory tract). Hemoptysis is the medical term for cough...
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Chest pain
Chest pain
Chest pain is discomfort or pain that you feel anywhere along the front of your body between your neck and upper abdomen.
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Cough
Cough
Coughing is an important way to keep your throat and airways clear. But too much coughing may mean you have a disease or disorder. Some coughs are d...
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Shortness of breath
Shortness of breath
Breathing difficulty may involve:Difficult breathingUncomfortable breathingFeeling like you are not getting enough air
- Weakness
- Weight loss
In most cases, there are no lung-related symptoms when the tumors are found.
Exams and Tests
The health care provider will examine you and ask about your medical history and symptoms. Tests that may be done include:
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Bronchoscopy
to view the airways
Bronchoscopy
Bronchoscopy is a test to view the airways and diagnose lung disease. It may also be used during the treatment of some lung conditions.
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Chest CT scan
Chest CT scan
A chest CT (computed tomography) scan is an imaging method that uses x-rays to create cross-sectional pictures of the chest and upper abdomen....
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Chest x-ray
Chest x-ray
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.
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Cytologic studies of pleural fluid
or sputum
Cytologic studies of pleural fluid
A cytology exam of pleural fluid is a laboratory test to detect cancer cells and certain other cells in the area that surrounds the lungs. This area...
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Lung needle biopsy
Lung needle biopsy
A lung needle biopsy is a method to remove a piece of lung tissue for examination. If it is done through the wall of your chest, it is called a tran...
- Surgery to take a sample of tissue from the lungs (surgical lung biopsy)
Treatment
Chemotherapy is used to treat metastatic cancer to the lung. Surgery to remove the tumors may be done when any of the following occurs:
- The first (primary) tumor has been removed
- The cancer has spread to only limited areas of the lung
- The lung tumors can be completely removed with surgery
However, the main tumor must be curable, and the person must be strong enough to go through the surgery and recovery.
Less common treatments include:
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Radiation therapy
Radiation therapy
Radiation therapy uses high-powered x-rays, particles, or radioactive seeds to kill cancer cells.
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The placement of
stents
inside the airways
Stents
A stent is a tiny tube placed into a hollow structure in your body. This structure can be an artery, a blood vessel, or something such as the tube t...
- Laser therapy
Experimental treatments may be recommended, such as:
- Using local heat probes to destroy the area.
- Placing chemotherapy medicines directly into the artery that supplies blood to the part of the lung containing the tumor.
Support Groups
You can ease the stress of illness by joining a support group where members share common experiences and problems.
Support group
The following organizations are good resources for information on cancer:American Cancer Society -- www. cancer. orgCancerCare -- www. cancercare. or...
Outlook (Prognosis)
A cure is unlikely in most cases of cancers that have spread to the lungs. But the outlook depends on the main cancer. Some cancers, such as lymphoma, are very treatable, and even curable. In rare cases, a person can live more than 5 years with metastatic cancer to the lungs.
You and your family may want to start thinking about end-of-life planning, such as:
- Palliative care
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Hospice care
Hospice care
Hospice care helps people with illnesses that cannot be cured and who are nearing death. The goal is to give comfort and peace instead of a cure. H...
-
Advance care directives
Advance care directives
Living will; Power of attorney; DNR - advance directive; Do not resuscitate - advance directive; Do-not-resuscitate - advance directive; Durable powe...
- Health care agents
Possible Complications
Complications of metastatic tumors in the lungs may include:
- Fluid between the lung and chest wall (pleural effusion), which can cause shortness of breath or pain when taking a deep breath
- Further spread of the cancer
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Side effects of
chemotherapy
or radiation therapy
Chemotherapy
The term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancerShrink the cancerPrevent the cancer from ...
When to Contact a Medical Professional
Call your provider if you have a history of cancer and you develop:
- Coughing up blood
- Persistent cough
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Shortness of breath
Shortness of breath
Breathing difficulty may involve:Difficult breathingUncomfortable breathingFeeling like you are not getting enough air
- Unexplained weight loss
Prevention
Not all cancers can be prevented. However, many can be prevented by:
- Eating healthy foods
- Exercising regularly
- Limiting alcohol consumption
- Not smoking
References
Arenberg DA, Pickens A. Metastatic malignant tumors. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 55.
Putnam JB. Lung, chest wall, and mediastinum. In: Townsend CM, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery . 20th ed. Philadelphia, PA: Elsevier; 2017:chap 57.
Ripley RT, Rusch VW. Lung metastases. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology . 5th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 52.
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Bronchoscopy - illustration
Bronchoscopy is a surgical technique for viewing the interior of the airways. Using sophisticated flexible fiber optic instruments, surgeons are able to explore the trachea, main stem bronchi, and some of the small bronchi. In children, this procedure may be used to remove foreign objects that have been inhaled. In adults, the procedure is most often used to take samples of (biopsy) suspicious lesions and for culturing specific areas in the lung.
Bronchoscopy
illustration
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Lung cancer, lateral chest x-ray - illustration
A lateral view of a chest x-ray in a patient with central cancer of the lung.
Lung cancer, lateral chest x-ray
illustration
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Lung cancer, frontal chest X-ray - illustration
A chest x-ray in a patient with central cancer of the right lung. Notice the white mass in the middle portion of the right lung (seen on the left side of the picture).
Lung cancer, frontal chest X-ray
illustration
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Coal workers pneumoconiosis - stage II - illustration
This chest x-ray shows stage II coal worker's pneumoconiosis (CWP). There are diffuse, small light areas on both sides of the lungs. Other diseases that may explain these x-ray findings include simple silicosis, disseminated tuberculosis, metastatic lung cancer, and other diffuse, infiltrative pulmonary diseases.
Coal workers pneumoconiosis - stage II
illustration
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Coal workers pneumoconiosis - stage II - illustration
This chest x-ray shows coal workers pneumoconiosis - stage II. There are diffuse, small (2 to 4 mm each), light areas throughout both lungs. In the right upper lung (seen on the left side of the picture), there is a light area (measuring approximately 2 cm by 4 cm) with poorly defined borders, representing coalescence (merging together) of previously distinct light areas. Diseases which may explain these x-ray findings include simple coal workers pneumoconiosis (CWP) - stage II, silico-tuberculosis, disseminated tuberculosis, metastatic lung cancer, and other diffuse infiltrative pulmonary diseases.
Coal workers pneumoconiosis - stage II
illustration
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Coal workers pneumoconiosis, complicated - illustration
This picture shows complicated coal workers pneumoconiosis. There are diffuse, small, light areas (3 to 5 mm) in all areas on both sides of the lungs. There are large light areas which run together with poorly defined borders in the upper areas on both sides of the lungs. Diseases which may explain these X-ray findings include complicated coal workers pneumoconiosis (CWP), silico-tuberculosis, disseminated tuberculosis, metastatic lung cancer, and other diffuse infiltrative pulmonary diseases.
Coal workers pneumoconiosis, complicated
illustration
-
Coal workers pneumoconiosis, complicated - illustration
This picture shows complicated coal workers pneumoconiosis. There are diffuse, massive light areas that run together in the upper and middle parts of both lungs. These are superimposed on a background of small and poorly distinguishable light areas that are diffuse and located in both lungs. Diseases which may explain these x-ray findings include, but are not limited to: complicated coal workers pneumoconiosis (CWP), silico-tuberculosis, and metastatic lung cancer.
Coal workers pneumoconiosis, complicated
illustration
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Pulmonary nodule - front view chest x-ray - illustration
This x-ray shows a single lesion (pulmonary nodule) in the upper right lung (seen as a light area on the left side of the picture). The nodule has distinct borders (well-defined) and is uniform in density. Tuberculosis (TB) and other diseases can cause this type of lesion.
Pulmonary nodule - front view chest x-ray
illustration
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Pulmonary nodule, solitary - CT scan - illustration
This CT scan shows a single lesion (pulmonary nodule) in the right lung. This nodule is seen as the light circle in the upper portion of the dark area on the left side of the picture. A normal lung would look completely black in a CT scan.
Pulmonary nodule, solitary - CT scan
illustration
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Sarcoid, stage II - chest X-ray - illustration
Sarcoid causes damage to the lung tissue that heals by scarring. The film shows a diffuse milky and granular appearance in the normally dark lung areas. This individual has marked decrease in lung function.
Sarcoid, stage II - chest X-ray
illustration
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Lung with squamous cell cancer - CT scan - illustration
This CT scan shows a cross section of the lungs of a person with lung cancer. The two dark areas in the middle of the screen are the lungs. The light areas in the right lung represent the cancer (left side of picture).
Lung with squamous cell cancer - CT scan
illustration
-
Respiratory system - illustration
Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.
Respiratory system
illustration
-
Bronchoscopy - illustration
Bronchoscopy is a surgical technique for viewing the interior of the airways. Using sophisticated flexible fiber optic instruments, surgeons are able to explore the trachea, main stem bronchi, and some of the small bronchi. In children, this procedure may be used to remove foreign objects that have been inhaled. In adults, the procedure is most often used to take samples of (biopsy) suspicious lesions and for culturing specific areas in the lung.
Bronchoscopy
illustration
-
Lung cancer, lateral chest x-ray - illustration
A lateral view of a chest x-ray in a patient with central cancer of the lung.
Lung cancer, lateral chest x-ray
illustration
-
Lung cancer, frontal chest X-ray - illustration
A chest x-ray in a patient with central cancer of the right lung. Notice the white mass in the middle portion of the right lung (seen on the left side of the picture).
Lung cancer, frontal chest X-ray
illustration
-
Coal workers pneumoconiosis - stage II - illustration
This chest x-ray shows stage II coal worker's pneumoconiosis (CWP). There are diffuse, small light areas on both sides of the lungs. Other diseases that may explain these x-ray findings include simple silicosis, disseminated tuberculosis, metastatic lung cancer, and other diffuse, infiltrative pulmonary diseases.
Coal workers pneumoconiosis - stage II
illustration
-
Coal workers pneumoconiosis - stage II - illustration
This chest x-ray shows coal workers pneumoconiosis - stage II. There are diffuse, small (2 to 4 mm each), light areas throughout both lungs. In the right upper lung (seen on the left side of the picture), there is a light area (measuring approximately 2 cm by 4 cm) with poorly defined borders, representing coalescence (merging together) of previously distinct light areas. Diseases which may explain these x-ray findings include simple coal workers pneumoconiosis (CWP) - stage II, silico-tuberculosis, disseminated tuberculosis, metastatic lung cancer, and other diffuse infiltrative pulmonary diseases.
Coal workers pneumoconiosis - stage II
illustration
-
Coal workers pneumoconiosis, complicated - illustration
This picture shows complicated coal workers pneumoconiosis. There are diffuse, small, light areas (3 to 5 mm) in all areas on both sides of the lungs. There are large light areas which run together with poorly defined borders in the upper areas on both sides of the lungs. Diseases which may explain these X-ray findings include complicated coal workers pneumoconiosis (CWP), silico-tuberculosis, disseminated tuberculosis, metastatic lung cancer, and other diffuse infiltrative pulmonary diseases.
Coal workers pneumoconiosis, complicated
illustration
-
Coal workers pneumoconiosis, complicated - illustration
This picture shows complicated coal workers pneumoconiosis. There are diffuse, massive light areas that run together in the upper and middle parts of both lungs. These are superimposed on a background of small and poorly distinguishable light areas that are diffuse and located in both lungs. Diseases which may explain these x-ray findings include, but are not limited to: complicated coal workers pneumoconiosis (CWP), silico-tuberculosis, and metastatic lung cancer.
Coal workers pneumoconiosis, complicated
illustration
-
Pulmonary nodule - front view chest x-ray - illustration
This x-ray shows a single lesion (pulmonary nodule) in the upper right lung (seen as a light area on the left side of the picture). The nodule has distinct borders (well-defined) and is uniform in density. Tuberculosis (TB) and other diseases can cause this type of lesion.
Pulmonary nodule - front view chest x-ray
illustration
-
Pulmonary nodule, solitary - CT scan - illustration
This CT scan shows a single lesion (pulmonary nodule) in the right lung. This nodule is seen as the light circle in the upper portion of the dark area on the left side of the picture. A normal lung would look completely black in a CT scan.
Pulmonary nodule, solitary - CT scan
illustration
-
Sarcoid, stage II - chest X-ray - illustration
Sarcoid causes damage to the lung tissue that heals by scarring. The film shows a diffuse milky and granular appearance in the normally dark lung areas. This individual has marked decrease in lung function.
Sarcoid, stage II - chest X-ray
illustration
-
Lung with squamous cell cancer - CT scan - illustration
This CT scan shows a cross section of the lungs of a person with lung cancer. The two dark areas in the middle of the screen are the lungs. The light areas in the right lung represent the cancer (left side of picture).
Lung with squamous cell cancer - CT scan
illustration
-
Respiratory system - illustration
Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.
Respiratory system
illustration
Review Date: 5/20/2016
Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.