Drug Notes

Ivabradine (By mouth)

Ivabradine (eye-VAB-ra-deen)

Treats heart failure.

Brand Name(s):

Corlanor

When This Medicine Should Not Be Used:

How to Use This Medicine:

Tablet

• Your doctor will tell you how much medicine to use. Do not use more than directed.
• It is best to take this medicine with food or milk.
• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not use this medicine if you are also using clarithromycin, itraconazole, nefazodone, nelfinavir, or telithromycin.
• Some foods and medicine can affect how ivabradine works. Tell your doctor if you are using any of the following:
  • Amiodarone, digoxin, diltiazem, phenobarbital, phenytoin, rifampicin, St John's wort, verapamil
  • Beta-blocker medicine
• Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

Warnings While Using This Medicine:

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
• Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart disease, low blood pressure, or heart rhythm problems. Tell your doctor if you have a pacemaker.
• This medicine may increase your risk of atrial fibrillation (uneven heartbeat) or bradycardia (slow heartbeat).
• This medicine may cause vision changes, such as temporary brightness. Be careful when you use machines or drive a car, especially when driving at night.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain or trouble breathing
• Fainting, dizziness, or lightheadedness
• Fast, slow, pounding, or uneven heartbeat
• Unusual tiredness or weakness

If you notice these less serious side effects, talk with your doctor:

• Temporary brightness of your vision

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/27/2017