Edoxaban (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to edoxaban.

Your doctor will tell you how much medicine to use. Do not use more than directed.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Some medicines can affect how edoxaban works. Tell your doctor if you are using any of the following:
- Rifampin
- Another blood thinner (including clopidogrel, heparin, prasugrel, warfarin)
- NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
- Medicine to treat depression (including citalopram, desvenlafaxine, duloxetine, escitalopram, fluoxetine, paroxetine, sertraline, venlafaxine)

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bleeding problems, spine problems, or a history of back surgery, heart valve disease, or an artificial heart valve.
This medicine may cause the following problems:
- Increased risk for bleeding
- Increased risk for blood clots in your spine or back after a spinal procedure
Do not stop using this medicine suddenly without asking your doctor . You risk of stroke is higher if you stop using this medicine suddenly.
Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests. Your doctor will tell you how to do this safely.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Back pain, numbness, tingling, or muscle weakness in your legs or feet, loss of bladder or bowel control
Bleeding from your gums or nose, heavy menstrual bleeding
Bleeding that does not stop, bruising, or weakness
Coughing up blood, vomiting blood or material that looks like coffee grounds
Pink or red urine, red or black stools
Sudden or severe headache, confusion, nausea

Last Updated: 1/27/2017