Atazanavir/cobicistat (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to atazanavir or cobicistat.

Your doctor will tell you how much medicine to use. Do not use more than directed.
It is best to take this medicine with food or milk.
Contact your doctor or pharmacist when your supply of this medicine is low. Do not allow yourself to run out of this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: If you miss a dose and it has been less than 12 hours , take the missed dose right away. If it has been more than 12 hours , skip the missed dose and take the next dose at your usual time. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

You must avoid many other medicines while you are using cobicistat with atazanavir. These medicines used together could cause serious health problems, including death. Medicines you must avoid include the following: alfuzosin, carbamazepine, cisapride, colchicine, dronedarone, indinavir, irinotecan, lovastatin, lurasidone, midazolam, nevirapine, phenobarbital, phenytoin, pimozide, ranolazine, rifampin, sildenafil for pulmonary hypertension, simvastatin, St John's wort, triazolam, and ergot medicines (including dihydroergotamine, ergotamine, methylergonovine).
There are many other drugs that can interact with this medicine. Ask your doctor before you use any other medicine.
If you take antacids that contain aluminum or magnesium, take them 2 hours before or 2 hours after you take this medicine.

Tell your doctor if you are pregnant, or if you have kidney problems, liver disease, diabetes, heart rhythm problems, or hemophilia.
Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.
This medicine may cause the following problems:
- Heart rhythm problems
- New or worsening kidney problems
- Kidney stones or gallstones
- Liver problems
Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.
Do not stop using this medicine unless your doctor tells you to. If you stop the medicine even for a short time, the virus may become harder to treat.
This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, red skin rash
Change in how much or how often you urinate, red or pink urine, lower back or side pain
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Fast, pounding, or uneven heartbeat, dizziness or lightheadedness

Last Updated: 1/27/2017