Fluocinolone/hydroquinone/tretinoin (On the skin)

There may be other brand names for this medicine.

Do not use this medicine if you have had an allergic reaction to fluocinolone, hydroquinone, or tretinoin.

Your doctor will tell you how much medicine to use. Do not use more than directed. Apply the medicine at least 30 minutes before bedtime.
Use this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
Wash your hands with soap and water before and after you use this medicine.
Wash your face and neck with warm water and a mild cleanser. Rinse well and pat dry.
Apply a thin layer of the medicine to the affected area. Rub it in gently.
Do not cover the treated area with a bandage unless directed by your doctor.
This medicine is not for long-term use.

Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

Store the medicine in the refrigerator. Do not freeze.
Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Make sure your doctor knows if you are pregnant or breastfeeding. Tell your doctor right away if you become pregnant while you are using this medicine. Tell your doctor if you have Cushing syndrome or diabetes. Tell your doctor if you are allergic to sulfites.
This medicine may cause a condition called exogenous ochronosis, a blue-black discoloration of the skin. Check with your doctor right away if you have a gradual darkening of the skin.
This medicine may make your skin more sensitive to sunlight, wind, and cold weather. Avoid sunlamps and tanning beds. Use a sunscreen with a sun protection factor of SPF 30 or higher during the day. Wear protective clothing, such as a hat, when you are outdoors.
Dry or red skin, peeling, burning, or itching can occur. Avoid cleansers or cosmetics that may dry or irritate your skin. Use a moisturizer as needed.
If you have a sunburn, stop using this medicine until your skin is healed.
Do not use this medicine to treat a skin problem your doctor has not examined.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blue-black darkening of the skin
Color changes on the skin, dark freckles, easy bruising, muscle weakness
Irritation around your eyes, nose, or mouth
Round, puffy face
Severe or ongoing skin redness, burning, peeling, blistering, crusting, or swelling

Last Updated: 1/27/2017