Avanafil (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to avanafil.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Take this medicine about 15 minutes before you have sex. Do not take it more than once a day. Always allow at least 24 hours between doses.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Do not use this medicine if you also use a nitrate medicine, often used to treat angina or high blood pressure. Nitrate medicines include nitroglycerin, isosorbide, amyl nitrate, butyl nitrate, and nitrite. Do not use this medicine if you also use riociguat.
Some foods and medicines can affect how avanafil works. Tell your doctor if you are using any of the following:
- Amprenavir, aprepitant, atazanavir, clarithromycin, desipramine, erythromycin, fluconazole, fosamprenavir, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, omeprazole, ritonavir, rosiglitazone, saquinavir, telithromycin
- Medicine to treat high blood pressure or prostate problems (including alfuzosin, amlodipine, diltiazem, doxazosin, enalapril, prazosin, silodosin, tamsulosin, terazosin, verapamil)
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

Tell your doctor if you have kidney disease, liver disease, bleeding problems, diabetes, heart or blood vessel disease, high blood pressure, high cholesterol, vision or eye problems, a stomach ulcer, or a penis with an abnormal shape. Tell your doctor if you have sickle cell anemia, leukemia, or multiple myeloma.
Tell your doctor if you ever had chest pain during sex, or you had a stroke or heart attack within the past 6 months.
Tell your doctor if you use any other medicine that might cause low blood pressure, because avanafil might also lower your blood pressure. If your blood pressure gets too low, you might faint or have other health problems.
Tell your doctor if you drink alcohol. You are more likely to have a drop in blood pressure if you have more than 3 drinks of alcohol at a time while you are taking this medicine.
This medicine may cause your penis to become erect when you do not want an erection or to stay erect for longer than you want.
This medicine will not protect you from sexually transmitted infections (including HIV or AIDS).
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain, especially if it spreads to your jaw or arm, trouble breathing, nausea, unusual sweating
Erection that is painful or lasts longer than 4 hours
Fast, pounding, or uneven heartbeat
Lightheadedness or fainting
Sudden hearing loss, ringing in your ears, or dizziness
Sudden loss of vision in one or both eyes

Last Updated: 1/27/2017