Drug Notes

Vilazodone (By mouth)

Vilazodone (vil-AZ-oh-done)

Treats depression.

Brand Name(s):

Viibryd, Viibryd Starter Pack

When This Medicine Should Not Be Used:

How to Use This Medicine:

Tablet

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
• It is best to take this medicine with food or milk.
• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Do not use this medicine if you have used an MAO inhibitor (MAOI) within the past 14 days.
• Some medicines can affect how vilazodone works. Tell your doctor if you are using any of the following:
  • Buspirone, carbamazepine, clarithromycin, digoxin, erythromycin, fentanyl, itraconazole, ketoconazole, lithium, phenytoin, rifampin, St John's wort, tramadol, tryptophan supplements, or voriconazole
  • Diuretic (water pill)
  • Blood thinner (including warfarin)
  • Medicine to treat migraine headaches
  • NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)

Warnings While Using This Medicine:

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, bleeding problems, glaucoma, or a history of seizures.
• For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
• This medicine may cause the following problems:
  • Serious drug reaction called serotonin syndrome (more likely when used with certain other medicines)
  • Increased risk of bleeding problems
  • Low sodium levels in the blood
• This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
• Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Agitation, irritability, sudden increase in energy, trouble sleeping
• Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there
• Confusion, weakness, muscle twitching
• Thoughts of hurting yourself or others, worsening depression, unusual behavior
• Unusual bleeding or bruising
• Vision changes, eye pain, seeing halos around lights

If you notice these less serious side effects, talk with your doctor:

• Mild diarrhea or nausea

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/27/2017