Cabazitaxel (By injection)

There may be other brand names for this medicine.

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to cabazitaxel or polysorbate 80 (a preservative).

Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
You may also receive other medicines to help prevent allergic reactions and nausea from the injection.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Some medicines can affect how cabazitaxel works. Tell your doctor if you are using any of the following:
- Atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole
- Blood thinner (including warfarin)
- NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
- Steroid (including dexamethasone, hydrocortisone, prednisolone)

Tell your doctor if you have kidney disease, liver disease, anemia, an infection, lung disease, or a history of stomach ulcer or bleeding.
This medicine can cause the following problems:
- Kidney problems
- Stomach and bowel problems (such as bleeding, perforation, inflammation, or blockage)
- Lung or breathing problems
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain, cough, trouble breathing
Constipation, severe nausea, vomiting, diarrhea, or stomach pain
Decrease in how much or how often you urinate, red or dark brown urine
Fever, chills, cough, sore throat, and body aches
Lightheadedness, dizziness, fainting
Numbness, tingling, or burning pain in your hands, arms, legs, or feet
Swelling in your hands, ankles, feet, or face
Unusual bleeding, bruising, or weakness

Mild nausea, vomiting, or diarrhea, loss of appetite
Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
Tiredness

Last Updated: 1/27/2017