Lubiprostone (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to lubiprostone, or if you have stomach or bowel blockage.

Your doctor will tell you how much medicine to use. Do not use more than directed.
Take this medicine with food and water. This will help lessen the chance of nausea.
Swallow the capsule whole. Do not crush, break, or chew it.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Some medicines can affect how lubiprostone works. Tell your doctor if you are using methadone or a blood pressure medicine.

Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, low blood pressure, severe diarrhea, or a sudden change in bowel movements.
This medicine may make you feel dizzy or lightheaded. Stand or sit up slowly if you are dizzy. This is more likely to happen when you begin to use the medicine or if you become dehydrated.
Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Lightheadedness, dizziness, fainting
Severe diarrhea, stomach pain or swelling
Severe nausea or vomiting
Trouble breathing

Last Updated: 1/27/2017