Sodium phenylbutyrate (By mouth)

There may be other brand names for this medicine.

You should not use this medicine if you or your child have had an allergic reaction to sodium phenylbutyrate.

Your doctor will tell you how much medicine to use. Do not use more than directed.
It is best to take this medicine with food or milk.
If you are using the oral powder , you can mix it with water or food (solid or liquid). Powder mixed with food should be used right away. Powder mixed in water can be stored for up to one week at room temperature or in the refrigerator.
Carefully follow your doctor's instructions about any special diet.

Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Make sure your doctor knows if you are using probenecid (Benemid®) or steroids (such as dexamethasone, prednisolone, prednisone, Celestone®, Cortone®, Decadron®, Deltasone®, or Pediapred®). Tell your doctor if you are also using haloperidol (Haldol®) or valproic acid (Depakene®).

Make sure your doctor knows if you are pregnant or breastfeeding, or if you have heart disease, kidney disease, liver disease, or edema (swelling from excess fluid).
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Decrease in how much or how often you urinate.
Heart rhythm problems.
Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
Severe menstrual bleeding.
Severe vomiting or rectal bleeding.
Sudden or severe stomach pain, nausea, vomiting, fever, or lightheadedness.
Swelling in your hand, ankles, or feet.
Unusual bleeding, bruising, or weakness.

Last Updated: 1/27/2017