Olmesartan/hydrochlorothiazide (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to olmesartan or hydrochlorothiazide, or if you are pregnant.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Do not use this medicine together with aliskiren.
Ask your doctor before you use any medicine, supplement, or salt substitute that contains potassium.
Some medicines can affect how this medicine works. Tell your doctor if you are using any of the following:
- Cholestyramine, colestipol, lithium
- ACE inhibitor blood pressure medicine
- Diuretic (water pill)
- Insulin or diabetes medicine
- NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)
- Steroid medicine (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)
If you also use colesevelam, take it at least 4 hours after you take this medicine.
Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine.

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
Tell your doctor if you are breastfeeding, or if you have kidney problems or trouble urinating, liver disease, heart failure, diabetes, glaucoma, gout, high cholesterol, lupus, or a history of asthma or allergies, including a sulfa or penicillin allergy.
This medicine may cause the following problems:
- Vision changes
- Kidney problems
- Low or high levels of minerals in your blood (including potassium and sodium)
This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel dizzy or lightheaded.
Drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting while you are using this medicine.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Change in how much or how often you urinate, bloody or cloudy urine
Confusion, weakness, muscle twitching
Dry mouth, increased thirst, muscle cramps, nausea, vomiting
Eye pain, vision changes, seeing halos around lights
Fast, slow, or uneven heartbeat, chest pain
Lightheadedness, dizziness, or fainting
Severe diarrhea with weight loss (could occur months to years after you start taking this medicine)

Last Updated: 1/27/2017