Naloxone (By injection)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to naloxone.

This medicine is given as a shot under your skin or into a muscle.
This medicine comes with patient instructions and a training device. You, your home health caregiver, and family members should read the instructions carefully. Ask your doctor if you have any questions.
Do not use the medicine if it is cloudy, discolored, or has large particles in it.
The autoinjector can be used only on time. Do not remove the red safety guard until you are ready to use it.
This medicine is available in 2 dosage strengths: 0.4 milligram (mg)/0.4 milliliter (mL) autoinjector and 2 mg/0.4mL autoinjector.
To use:
- Inject the medicine into the outer thigh, through clothing, if needed. If you are giving this medicine to a child younger than 1 year of age, pinch the thigh while you give the medicine.
- After you give the first dose to the patient, get emergency medical help right away .
- Closely watch the patient after the injection for signs and symptoms of an opioid emergency.
- Give a new injection every 2 to 3 minutes if symptoms return.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or heart disease.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Crying more than the usual (in babies)
Diarrhea, nausea, vomiting, stomach cramps
Fast, pounding, or uneven heartbeat, trouble breathing
Fever, runny nose, sneezing, sweating, yawning
Seizures, tremors, feeling restless, nervous, or irritable

Last Updated: 1/27/2017