Acyclovir cream (On the skin)

Acyclovir (ay-SYE-kloe-vir)

Treats herpes labialis (cold sores).

Brand Name(s):

Zovirax

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to acyclovir or similar medicines (such as valacyclovir). Do not use this medicine to treat genital herpes.

How to Use This Medicine:

Cream

Use this medicine as soon as possible after you notice the beginning of a cold sore (tingle, pain, burning, blisters, or itching).
This medicine is for use on your face or lips only. Do not get it in your eyes, or inside your mouth or nose.
Wash your hands with soap and water before and after you use this medicine.
Apply a thin layer of the medicine to the affected area. Rub it in gently.
Do not cover the treated area with a bandage unless directed by your doctor.

If a dose is missed:

Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

Store this medicine at room temperature, away from heat and direct light.
Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Do not put cosmetics or skin care products on the treated skin.

Warnings While Using This Medicine:

Make sure your doctor knows if you are pregnant or breast feeding.
This medicine should not be used on a child under 12 years old unless your doctor tells you to.
Do not use this medicine to treat a skin problem your doctor has not examined.

Possible Side Effects While Using This Medicine:

If you notice these less serious side effects, talk with your doctor:

Very dry, chapped, or cracked lips.
Itching, redness, swelling, burning, or stinging of your skin where the cream is applied.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/27/2017