Trovafloxacin (By mouth)

Trovafloxacin (troe-va-FLOX-a-sin)

Treats infections that are caused by bacteria. This medicine is a fluoroquinolone antibiotic. The marketing and distribution of trovafloxacin (and alatrofloxacin) have been discontinued.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to trovafloxacin or to similar medicines such as ciprofloxacin (Cipro®), enoxacin (Penetrex®), gatifloxacin (Tequin?), levofloxacin (Levaquin®), lomefloxacin (Maxaquin?), moxifloxacin (Avelox®), norfloxacin (Noroxin®), or ofloxacin (Floxin®). This medicine should not be given to children.

How to Use This Medicine:

Tablet

Your doctor will tell you how much medicine to use. Do not use more than directed.
Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.
You may take your medicine with food.
Drink extra fluids so you will urinate more often and help prevent kidney problems.

If a dose is missed:

Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Make sure your doctor knows if you are also using blood thinners (Coumadin®), omeprazole (Prilosec®), or theophylline.
If you are also using antacids, multivitamins (with calcium, iron, or zinc), sucralfate (Carafate®), or didanosine (Videx®) powder or chewable/buffered tablets, take these medicines at least 2 hours before or 2 hours after you take trovafloxacin .
Avoid caffeine (coffee, soda, chocolate) while you are using this medicine.

Warnings While Using This Medicine:

Make sure your doctor knows if you are pregnant or breastfeeding, or if you have a history of heart disease, heart rhythm problems, hypokalemia (low blood potassium), stroke, or seizure disorder (such as epilepsy).
This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
Call your doctor if you have pain, swelling, or tearing of a tendon, such as in the back of your knee or ankle, in your shoulder or elbow, or in your hand or wrist. You may need to stop taking the medicine.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain.
Dark colored urine, pale stools, yellow eyes or skin.
Diarrhea.
Fast or slow heartbeat.
Lightheadedness or fainting.
Seizures.
Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness.
Unusual bleeding or bruising, skin rash, redness, blistering, or peeling.

If you notice these less serious side effects, talk with your doctor:

Dizziness, nervousness, anxiety, confusion, or agitation.
Headache or tiredness.
Muscle or joint pain.
Nausea, vomiting, stomach pain, or constipation.
Nightmares or trouble sleeping.
Sores or white patches in your mouth or throat.
Vaginal itching or discharge.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/27/2017