Drug Notes

Cefoperazone (By injection)

Cefoperazone (sef-oh-PER-a-zone)

Treats infections caused by bacteria. Belongs to a class of drugs called cephalosporin antibiotics.

Brand Name(s):

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given.
• An IM injection is a shot given in your muscle (upper arm, thigh, buttocks). An IV infusion is medicine that is put directly into your body through one of your veins.
• This medicine should be given by a person trained to give IV or IM medicine, such as a nurse. Sometimes you, a family member, or friend can be taught to give your medicine.
• If you are receiving IV medicine, check the bag to make sure there are no leaks. Also make sure the solution is clear.

If a dose is missed:

• This medicine needs to be given on a regular schedule. Take the missed dose as soon as you remember, and take the rest of the doses for the day at regularly spaced time intervals.
• If you miss more than one dose, call your doctor for instructions.

How to Store and Dispose of This Medicine:

• Store in a refrigerator. Do not freeze. Take it out of the refrigerator an hour before the time for your next dose and allow it to warm to room temperature in a clean, dry place.
• If you see particles in the solution, You should not use it.
• If you have your treatments at home, you should be given a special container for the used needles. Keep it where children or pets cannot reach it.
• Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are taking a blood thinner such as Coumadin®.
• Do not drink alcohol while taking this medicine.

Warnings While Using This Medicine:

• If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
• Before taking this medicine, let your doctor know if you have ever had an allergic reaction to penicillin.
• Make sure your doctor knows if you have liver or kidney disease or if you have ever had colitis.
• If you have severe diarrhea while taking cefoperazone, check with your doctor before taking medicine to stop the diarrhea.
• If your infection does not improve, or if it gets worse, while taking this medicine, talk to your doctor.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Rash or hives
• Swelling of the face, throat, or lips
• Wheezing or trouble breathing
• Severe diarrhea (watery or bloody)
• Severe vomiting or stomach pain
• Swelling, pain, or redness near where your IV is located
• Unusual bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

• Mild diarrhea or nausea
• Vaginal itching or discharge
• Pain where the IM shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/27/2017