Tolazamide (By mouth)

Tolazamide (tole-AZ-a-mide)

Treats diabetes mellitus (sugar diabetes).Belongs to a class of drugs called sulfonylureas.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to tolazamide or to related medicine such as Orinase®, Diabinese®, or Glucotrol®.

How to Use This Medicine:

Tablet

Your doctor will tell you how much to take and how often.

If a dose is missed:

Take the missed dose as soon as possible.
Skip the missed dose if it is almost time for your next regular dose.
You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

Store at room temperature, away from heat, moisture, and direct light.
Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Avoid drinking alcohol while you are taking this medicine.
While using this medicine, avoid taking aspirin or cough and cold medicines.
Tolazamide interacts with many medicines. Before you start taking tolazamide, make sure your doctor knows of all other medicines that you are taking.

Warnings While Using This Medicine:

Talk with your doctor before taking tolazamide if you are pregnant, breastfeeding, or have liver or heart disease, G-6-PD deficiency, or an adrenal or pituitary gland disorder.
To control your diabetes, follow the diet that your doctor ordered and take this medicine on a regular schedule.
You may have low blood sugar while you are taking tolazamide, especially if you miss a meal, exercise for a long time, or drink alcohol. Symptoms of low blood sugar include sweating, feeling very hungry, fast heartbeat, drowsiness, confusion, headache that won't go away, chills, or vomiting.
Ask you doctor what you should do in case you have low blood sugar. You will need to control it quickly.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

Unexplained fever, chills, or sore throat
Unusual bleeding or bruising
Yellowing of skin or eyes
Dark urine

If you notice these less serious side effects, talk with your doctor:

Mild nausea or vomiting
Headache
Stomach pain or upset
Sensitivity of skin to sunlight
Skin rash or itching

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/27/2017