Metoprolol/hydrochlorothiazide (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to metoprolol, hydrochlorothiazide, or sulfa drugs.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Tablet: Take it with a meal or just after a meal.
Extended-release tablet: Take it with or without food. Swallow the extended-release tablet whole. Do not crush, break, or chew it.
Missed dose: If you miss a dose or forget to use your medicine, skip the missed dose. Never take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Some foods and medicines can affect how metoprolol/hydrochlorothiazide works. Tell your doctor if you use the following:
- Cholestyramine, cimetidine, clonidine, colestipol, digoxin, diphenhydramine, fluoxetine, hydroxychloroquine, lithium, methyldopa, paroxetine, propafenone, quinidine, reserpine, ritonavir, terbinafine, thioridazine
- Insulin or diabetes medicine
- MAO inhibitor (MAOI)
- NSAID pain or arthritis medicine (such as aspirin, diclofenac, indomethacin, naproxen)
- Steroid medicine (such as hydrocortisone, methylprednisolone, prednisolone, prednisone)
Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium.
Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, heart rhythm problems (such as bradycardia), glaucoma, gout, diabetes, lupus, an overactive thyroid, pheochromocytoma, trouble urinating, or a history of asthma or lung disease.
This medicine may cause new or worsening heart failure.
Do not stop using this medicine suddenly without asking your doctor , or you could develop life-threatening heart problems.
Tell any doctor or dentist who treats you that you are using this medicine, especially before you have any type of surgery.
This medicine may cause you to feel dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you are dizzy or lightheaded.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, red skin rash
Change in how much or how often you urinate
Chest pain that may spread, nausea, unusual sweating, fainting
Confusion, weakness, and muscle twitching
Dry mouth, increased thirst, or muscle cramps
Eye pain, vision changes, seeing halos around lights
Lightheadedness, dizziness, or fainting
Slow, fast, pounding, or uneven heartbeat
Sudden and severe stomach pain, nausea, or vomiting
Swelling in your hands, feet, ankles, or legs, tiredness
Trouble breathing or wheezing

Last Updated: 1/27/2017