Theophylline (By mouth)

There may be other brand names for this medicine.

You should not use this medicine if you have had an allergic reaction to theophylline.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Your doctor might need to test your blood each time the dose is changed.
You may take this medicine with or without food, but it might be best for you to take this medicine with a meal. Ask your doctor or pharmacist. It is important for you to take the medicine the same way every time. That means if you take your medicine with food, then you should always take it with food. If you take your medicine on an empty stomach, then you should always take it on an empty stomach.
It is best to take your medicine at the same time every day.
This medicine is available in several different forms. Sometimes the tablet or capsule has to be swallowed whole. Do not chew or crush any tablet or capsule that has to be swallowed whole. Sometimes the capsule can be opened and sprinkled on soft food. Sometimes the tablet has lines on it for you to break off a piece of the tablet. Ask your pharmacist how to take the specific kind of theophylline that you are using. Make sure you understand all the directions, so you will get the right amount of medicine.
Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
If you take the extended-release tablet, part of the tablet may pass into your stools. This is normal and is nothing to worry about.

Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

There are many other medicines that can interfere with theophylline. This includes nonprescription (over-the-counter) medicines and herbal products. Make sure your doctor knows about all other medicines you are using.
Other changes in your life might affect how much theophylline you need. However, do not change your dose of medicine unless your doctor tells you to. Make sure your doctor knows if you have any of these changes:
- Start or stop taking other medicines.
- Eating different foods, especially if you want to limit protein or carbohydrates ("carbs").
- Start or stop smoking, either you or someone you live with. This includes cigarettes or any other kind of tobacco, and marijuana.
Make sure your doctor knows if you smoke.
Tell your doctor if you eat beef that has been cooked over charcoal (such as on a grill) every day.
Do not use St. John's wort while you are being treated with theophylline.

Make sure your doctor knows if you are pregnant or breastfeeding, or if you have a stomach ulcer, seizures, or heart rhythm problems. Tell your doctor if you have liver disease, kidney disease, thyroid problems, or problems with your nervous system.
Make sure your doctor knows about any other lung or heart problems you have, including cor pulmonale, pulmonary hypertension, congestive heart failure (CHF), or cystic fibrosis.
Call your doctor if you start to run a fever or you get sick. An illness can change how much medicine you need. Your doctor will need to make sure you are not getting too much during the illness. Do not change your dose of medicine unless your doctor tells you to.
Tell your doctor about any changes you have in other on-going health problems. This includes health problems that you see a different doctor for.
If you start to have any serious side effects, do not take any more of this medicine until your doctor says it is okay.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You might need to have the blood drawn at a specific time of the day.
Make sure any doctor or dentist who treats you knows that you are using this medicine.
Tell your doctor if you start to have symptoms in between the times you take your medicine.
If you have a flare-up of breathing problems, do not use more theophylline. Ask your doctor if you should have another medicine to use when you have a flare-up of breathing problems.

Last Updated: 1/27/2017