Prochlorperazine (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to prochlorperazine or another phenothiazine medicine.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Some foods and medicines can affect how prochlorperazine works. Tell your doctor if you are also using any of the following:
- Lithium
- Blood thinner (such as warfarin)
- Diuretic (water pill)
- Blood pressure or heart medicine (such as guanethidine or propranolol)
- Medicine to treat seizures (such as phenytoin)
Do not drink alcohol while you are using this medicine.
Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, low blood pressure, glaucoma, seizures, or a history of breast cancer.
This medicine may cause the following problems:
- Tardive dyskinesia (a muscle disorder that could become permanent)
- Neuroleptic malignant syndrome (a nerve disorder that could be life-threatening)
- Extrapyramidal reaction (a muscle and nerve disorder)
- Overheating, because your body may not be able to cool down as it normally would
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Tell your doctor if you have bone marrow problems or if you have ever had a blood disorder, such as low blood cell counts.
Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine if you have a myelography.
If this medicine is being used by a child, tell the doctor if the child gets sick or becomes dehydrated (such as from vomiting and diarrhea). If the child becomes nervous and overly excited, do not give any more medicine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Dizziness, lightheadedness, or fainting
Jerky muscle movement you cannot control (often in your face, tongue, or jaw)
Fever, chills, cough, sore throat, and body aches
Fever, sweating, confusion, uneven heartbeat, muscle stiffness
Severe sleepiness
Unusual bleeding, bruising, or weakness
Yellow skin or eyes

Last Updated: 1/27/2017