Diclofenac (By mouth)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to diclofenac, aspirin, or another NSAID.

Your doctor will tell you how much medicine to use. Do not use more than directed.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Oral solution: Mix the packet contents with 1 to 2 ounces (30 to 60 mL) of water. Do not use any liquid other than water for mixing the medicine. Mix well and drink it immediately on an empty stomach.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. .

Do not use any other NSAID unless your doctor says it is okay. Some other NSAIDs are aspirin, diflunisal, ibuprofen, naproxen, or salsalate.
Some medicines and foods can affect how diclofenac works. Tell your doctor if you are also using any of the following:
- Cyclosporine, digoxin, lithium, methotrexate, pemetrexed
- Blood pressure medicine
- Blood thinner (such as warfarin)
- Diuretic (water pill)
- Medicine to treat depression
- Steroid medicine

Tell your doctor if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy, unless your doctor tells you to.
Tell your doctor if you have kidney disease, liver disease, asthma, heart failure, high blood pressure, or heart or blood vessel problems, or a history of stomach ulcers or bleeding problems. Tell your doctor if you have phenylketonuria (PKU). Also tell your doctor if you drink alcohol.
This medicine may cause the following problems:
- Increased risk of heart attack, heart failure, or stroke
- Bleeding in your stomach or intestines
- Liver problems
- Serious skin reactions
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Bloody or black, tarry stools, severe stomach pain, vomiting blood or material that looks like coffee grounds
Change in how much or how often you urinate
Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, unusual sweating, faintness
Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg, sudden or severe headache, or problems with vision, speech, or walking
Rapid weight gain, swelling in your hands, ankles, or feet

Last Updated: 1/27/2017