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    Aldosterone blood test

    The aldosterone blood test measures the level of the hormone aldosterone in blood.

    Aldosterone can also be measured using a urine test.

    How the Test is Performed

    A blood sample is needed.

    How to Prepare for the Test

    Your health care provider will ask you to stop for a short time medicines that may affect the test results. Be sure to tell your provider about all the medicines you take. These include:

    • High blood pressure medicines
    • Heart medicines
    • Nonsteroidal anti-inflammatory drugs (NSAIDs)
    • Antacid and ulcer medicines
    • Water pills (diuretics)

    Do not stop taking any medicine before talking to your doctor.Your health care provider may recommend that you eat no more than 3 grams of salt (sodium) per day for at least 2 weeks before the test.

    Or, your provider will recommend that you eat your usual amount of salt and also test the amount of sodium in your urine.

    At other times,the aldosterone blood test is done right before and after you receive a salt solution (saline)through the vein (IV) for 2 hours. Be aware that other factors can affect aldosterone measurements, including:

    • Pregnancy
    • High- or low-sodium diet
    • Strenuous exercise
    • Stress

    How the Test Will Feel

    When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. These soon go away.

    Why the Test is Performed

    This test is ordered for the following conditions:

    • Certain fluid and electrolyte disorders
    • Hard to control blood pressure
    • Low blood pressure upon standing (orthostatic hypotension)

    Aldosterone is a hormone released by the adrenal glands. It helps the body regulate blood pressure. Aldosterone increases the reabsorption of sodium and water and the release of potassium in the kidneys. This action raises blood pressure.

    Aldosterone blood test is often combined with other tests, such as the renin hormone test, to diagnose over- or under-production of aldosterone.

    Normal Results

    Normal levels vary:

    • Between children, teens, and adults
    • Depending on whether you were standing, sitting, or lying down when the blood was drawn

    Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test results.

    What Abnormal Results Mean

    A higher than normal level of aldosterone may be due to:

    • Bartter syndrome (extremely rare)
    • Adrenal glands release too much aldosterone hormone (primary hyperaldosteronism - usually due to a benign nodule in the adrenal gland)
    • Very low-sodium diet

    A lower than normal level of aldosterone may be due to:

    • Adrenal gland disorders, including not releasing enough aldosterone, and a condition called primary adrenal insufficiency (Addison disease)
    • Very high-sodium diet

    Risks

    Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

    Other risks associated with having blood drawn are slight but may include:

    • Excessive bleeding
    • Fainting or feeling lightheaded
    • Hematoma (blood accumulating under the skin)
    • Infection (a slight risk any time the skin is broken)

    References

    Gruber HA, Farag AF. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 24

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              Tests for Aldosterone blood test

              Review Date: 9/1/2013

              Reviewed By: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.

              The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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