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    24-hour urinary aldosterone excretion test

    Aldosterone - urine

    The 24-hour urinary aldosterone excretion test measures the amount of aldosterone removed in the urine in a day.

    Aldosterone can also be measured with a blood test.

    How the Test is Performed

    A 24-hour urine sample is needed. You will need to collect your urine over 24 hours. Your health care provider will tell you how to do this. Follow instructions exactly. This ensures accurate results.

    How to Prepare for the Test

    Your health care provider will ask you to stop for a short time medicines that may affect the test results. Be sure to tell your provider about all the medicines you take. These include:

    • High blood pressure medicines
    • Heart medicines
    • Nonsteroidal anti-inflammatory drugs (NSAIDs)
    • Antacid and ulcer medicines
    • Water pills (diuretics)

    Do not stop taking any medicine before talking to your doctor.

    Be aware that other factors can affect aldosterone measurements, including:

    • Pregnancy
    • High- or low-sodium diet
    • Strenuous exercise
    • Stress

    Do not drink coffee, tea, or cola during urine collection. Your health care provider will likely recommend that you eat no more than 3 grams of salt (sodium) per day for at least 2 weeks before the test.

    How the Test Will Feel

    The test involves only normal urination. There is no discomfort.

    Why the Test is Performed

    The test is done to see how much aldosterone is released into your urine. Aldosterone is a hormone released by the adrenal gland that helps the kidney control salt and potassium balance.

    Normal Results

    Results depend on:

    • How much sodium is in your diet
    • Whether your kidneys work properly
    • The condition being diagnosed

    Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor about the meaning of your specific test results.

    What Abnormal Results Mean

    A higherthan normal level of aldosterone may be due to:

    • Abuse of diuretics ("water pills")
    • Liver cirrhosis
    • Adrenalgland problems
    • Heart failure
    • Laxative abuse

    Lower than normal levels may indicate Addison disease.

    Risks

    There are no risks with this test.

    References

    Gruber HA, Farag AF. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 24.

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                Tests for 24-hour urinary aldosterone excretion test

                Review Date: 9/1/2013

                Reviewed By: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.

                The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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                St. Luke's Hospital - 232 South Woods Mill Road - Chesterfield, MO 63017 Main Number: 314-434-1500 Emergency Dept: 314-205-6990 Patient Billing: 888-924-9200
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